Using aging chamber to screen mechanical and electronic components can effectively improve the reliability of products. The uniformity of the temperature and humidity field inside the aging chamber determines its overall performance, which has a crucial impact on the functionality of the aging chamber. With the goal of enhancing the performance of the aging chamber, the simulation was conducted on the simplified model of aging chamber by using CFD (computational fluid dynamics) software based on the fluid dynamics principle. According to the simulation results, the distribution of velocity field and temperature field inside the aging chamber was determined to optimize the air supply scheme under the combination of different air supply temperature, air supply speed and air supply angle. The orthogonal test method was adopted in the simulation test, with air supply temperature, air supply speed and air supply angle as test factors, and energy utilization coefficient, temperature non-uniformity coefficient and relative humidity non-uniformity coefficient as evaluation indexes. Through range and variance analysis of simulation results, it could be seen that the influence of air supply angle on energy utilization coefficient was the most significant, and the influence of air supply temperature on temperature non-uniformity coefficient and relative humidity non-uniformity coefficient was the most significant. For the three evaluation indexes, three optimal schemes were obtained: air supply temperature of 90 ℃, air supply speed of 10 m/s, air supply angle of 0°, air supply temperature of 90 ℃, air supply speed of 12 m/s, air supply angle of -10°, and air supply temperature of 90 ℃, air supply speed of 8 m/s, air supply angle of 0°. Finally, the temperature and humidity measurement experiment inside the aging chamber was carried out and compared with the simulation results. The results showed that the relative errors between the simulation results and the experimental results were small and within a reasonable range, which verified the reliability and effectiveness of the simulation test. The research is oriented to improve the performance and energy utilization of aging chamber, which can provide reference for the design of similar aging chambers and the setting of air supply parameters.