Structural design of novel three-layer figure-of-8 coil for transcranial magnetic stimulation

doi:10.3785/j.issn.1008-973X.2021.04.022

Journal of ZheJiang University (Engineering Science)

2021, Vol. 55

Issue (4): 793-800 DOI: 10.3785/j.issn.1008-973X.2021.04.022

Structural design of novel three-layer figure-of-8 coil for transcranial magnetic stimulation

Hui XIONG(

),Zhao JING,Jin-zhen LIU

1. School of Electrical Engineering and Automation, TIANGONG University, Tianjin 300387, China
2. Tianjin Key Laboratory of Advanced Technology of Electrical Engineering and Energy, TIANGONG University, Tianjin 300387, China

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Abstract

A new three-layer figure-of-8 coil with the special structure and current direction was designed and optimized based on the superposition and cancellation of magnetic field. COMSOL simulation software was used to analyze the effects of the three-layer figure-of-8 coil with the changing of size and the rotation angle along the tangent line on the stimulation performance, and the coil structure was optimized. The stimulation intensity of the optimized three-layer figure-of-8 coil was increased by 33.92% and the focality was improved by 25.43% compared with figure-of-8 coil. Results show that the three-layer figure-of-8 coil has better stimulation intensity and focality at a certain target position. Then the adverse effects of non-target areas were greatly reduced, and the safety of TMS treatment was guaranteed. The performance advantages of the optimized three-layer-8-shaped coil were verified by stimulating the realistic head model.

Key words： transcranial magnetic stimulation three-layer figure-of-8 coil focality stimulation depth stimulation intensity

Received: 01 April 2020 Published: 07 May 2021

CLC:	R 318
	R 856

Fund: 国家自然科学基金资助项目（61871288）；天津市高等学校创新团队培养计划资助项目（TD13-5036）；天津市自然科学基金资助项目（18JCYBJC 90400，18JCQNJC84000）

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	Hui XIONG
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Cite this article:

Hui XIONG,Zhao JING,Jin-zhen LIU. Structural design of novel three-layer figure-of-8 coil for transcranial magnetic stimulation. Journal of ZheJiang University (Engineering Science), 2021, 55(4): 793-800.

URL:

http://www.zjujournals.com/eng/10.3785/j.issn.1008-973X.2021.04.022 OR http://www.zjujournals.com/eng/Y2021/V55/I4/793

新型经颅磁刺激三层-8字形线圈的结构设计

基于磁场的叠加与抵消，设计与优化具有特殊结构和电流方向的三层-8字形线圈. 利用COMSOL仿真软件，分析三层-8字形线圈尺寸和沿切线旋转角度的改变对刺激性能的影响，优化线圈结构. 与8字形线圈相比，优化后的三层-8字形线圈的刺激强度提高33.92%，聚焦性提高25.43%. 结果表明，在目标靶点处，优化后三层-8字形线圈具有更强的刺激强度和聚焦性，有效减弱对非目标区域的不良影响，保证TMS治疗的安全性. 通过刺激真实头部模型，验证优化后三层-8字形线圈的性能优势.

关键词： 经颅磁刺激, 三层-8字形线圈, 聚焦性, 刺激深度, 刺激强度

Fig.1 Two layers ball-shaped head model with stimulation coils

Fig.2 Three-layer figure-of-8 coil with different stimulating current directions and radii as well as three types of structures rotating along tangent

Tab.1 Seven types of coils with various outer radii

Tab.2 Stimulation calculation results of three different coils

Fig.3 Relation between maximum electric field strength，rotation angel θ and radius

Fig.4 Relation between stimulation depth，rotation angel θ and radius

Fig.5 Relation between focusing area，rotation angel θ and radius

Fig.6 Electric field strength distribution induced by optimal three-layer figure-of-8 coil at cerebral cortex

Tab.3 Stimulation calculation results of figure-of-8 and three-layer figure-of-8 coil before and after optimization

Fig.7 Structure of realistic head model

Fig.8 Induced electric field strength distribution map of three coils based on realistic head model


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