It’s very difficult to construct the complex microstructure of clay. A multiparameter random generationgrowth method, quartet structure generation set (QSGS) was introduced to model the microstructure of clay. The basic principle of QSGS was introduced, and the generation step of QSGS was constructed. The corresponding procedures were compiled with Matlab and AutoCAD VBA. The impact of the structure of clay microstructure on groundwater seepage was discussed by a case study. The microstructure of clay generated by QSGS can be directly imported into finite element method, and many issues of the microscale can be analyzed by numerical analysis software. The size distribution, shapes, micropore structure, circuitous of the constructed clay particle were quite similar to the real microstructure of clay.
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