Please wait a minute...
浙江大学学报(工学版)
生物医学工程、化学工程     
腕戴式低功耗无线心率监测装置的研制
周聪聪1, 涂春龙1, 高云1, 王飞翔1, 何成1, 龚红伟2,连平2, 叶学松1,3
1. 浙江大学 生物医学工程学系,浙江 杭州310027;2.解放军第85医院,上海 200052;3.浙江大学 唐仲英传感材料及应用研究中心,浙江 杭州 310027
Low power, wireless, wrist-worn device for HR monitoring based on double channels of pulse sensing
ZHOU Cong-cong1, TU Chun-long1, GAO Yun1, WANG Fei-xiang1, HE Cheng1, GONG Hong-wei2, LIAN Ping2, YE Xue-song1,3
1. Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China; 2. No. 85 Hospital of People’s Liberation Army, Shanghai 200052, China; 3. Cyrus Tang Center for Sensor Materials and Applications, Zhejiang University, Hangzhou 310058, China
 全文: PDF(2051 KB)   HTML
摘要:

研制新型的基于双通道脉搏传感的腕戴式无线低功耗心率实时监测装置.根据人体腕部生理解剖的特点,提出桡动脉、尺动脉双通道脉搏波及差分信号同步检测的新方法.研制了集传感器、调理电路、微处理器、通讯、自动增益算法和心率算法等软、硬件部件于一体的小型化装置.电路系统测试表明:在待机和工作模式下的平均工作电流分别约为10和300 μA;对10名男性在休憩状态下的心率进行3 h的连续动态监测,将测试结果与标准动态心电图记录的数据进行比较,结果表明,心率测量的算术平均误差约为0.3 BPM.

Abstract:

A new low-power wrist-worn miniature device used for real-time wireless heart rate (HR) monitoring was presented. A novel pulse signal detection method based on double channels of pulse sensing of the radial artery and ulnar artery as well as their differential signal was proposed. A miniature device consisting of sensors, signal condition system was fabricated. The micro-controller is responsible for power administration, and calculation of auto gain control algorithm and heart rate algorithms. The average currents are about 10 μA and 300 μA in standby and active modes, respectively. Ten male subjects were selected to test the performance of the device through a three-hour continuous test in their resting condition with the reference of a Holter monitor. The HR of the device was compared with the HR from the ECG signal recorded by the Holter monitor. The experimental results indicate that the arithmetical average error is about 0.3 BPM.

出版日期: 2015-04-01
:  R 318  
基金资助:

“十一五”全军重大专项资助项目(W08Z008);国家“863”高科技支撑计划资助项目(2012BAH06F00);国家科技支撑计划课题(2012BAI14B06)

通讯作者: 叶学松,男,教授,博导     E-mail: yexuesong@zju.edu.cn
作者简介: 周聪聪(1987—), 男, 博士生, 从事穿戴式医疗仪器的研究.E-mail:11015014@zju.edu.cn
服务  
把本文推荐给朋友
加入引用管理器
E-mail Alert
RSS
作者相关文章  

引用本文:

周聪聪, 涂春龙, 高云, 王飞翔, 何成, 龚红伟,连平, 叶学松. 腕戴式低功耗无线心率监测装置的研制[J]. 浙江大学学报(工学版), 10.3785/j.issn.1008-973X.2015.04.027.

ZHOU Cong-cong, TU Chun-long, GAO Yun, WANG Fei-xiang, HE Cheng, GONG Hong-wei, LIAN Ping, YE Xue-song. Low power, wireless, wrist-worn device for HR monitoring based on double channels of pulse sensing. JOURNAL OF ZHEJIANG UNIVERSITY (ENGINEERING SCIENCE), 10.3785/j.issn.1008-973X.2015.04.027.

链接本文:

http://www.zjujournals.com/eng/CN/10.3785/j.issn.1008-973X.2015.04.027        http://www.zjujournals.com/eng/CN/Y2015/V49/I4/798

[1] GABRIEL H. Reappraisal of the importance of heart rate as a risk factor for cardiovascular morbidity and mortality \[J\]. Clinical Therapeutics, 1997, 19(1): 39-52.
[2] FOX K, BORER J S, CAMM A J, et al. Resting heart rate in cardiovascular disease \[J\]. Journal of the American College of Cardiology, 2007, 50(9): 823-830.
[3] CHRISTINE P G,LAURE J, ATHANASE B. Heart rate as a risk factor for cardiovascular disease \[J\]. Progress in Cardiovascular Diseases, 2009, 52(1): 610.
[4] PAOLO P. Elevated heart rate: a “new” cardiovascular risk factor  \[J\]. Progress in Cardiovascular Diseases, 2009, 52(1): 15.
[5] FOSBOL E L, SEIBAEK M, BENTE B, et al. Long-term prognostic importance of resting heart rate in patients with left ventricular dysfunction in connection with either heart failure or myocardial infarction: the DIAMOND study \[J\]. International Journal of Cardiology, 2010, 140(3): 279-286.
[6] LIPINSKI M J, VETROVEC G W, GORELIK D, et al. The importance of heart rate recovery in patients with heart failure or left ventricular systolic dysfunction \[J\]. Journal of Cardiac Failure, 2005, 11(8): 624-630.
[7] MADDOX T M, ROSS C, MASOUDIET F A, et al. The prognostic importance of abnormal heart rate recovery and chronotropic response among exercise treadmill test patients \[J\]. American Heart Journal, 2008, 156(4): 736-744.
[8] GROFF C P, MULVANEY P L. Vital sign monitoring system of e.g. body temperature of in-patient, has CPU which statistically analyzes detected vital signs data and determines abnormal vital sign condition from normal condition: US6102856-A \[P\]. 20000815.
[9] ANH D, DANIEL T, LI C, et al. A wearable device for physical activity monitoring with built-in heart rate variability \[C\]∥ 3rd International Conference on Bioinformatics and Biomedical Engineering. Beijing: \[s. n.\], 2009: 14.
[10] HASHEM M M A, SHAMS R, KADER M A, et al. Design and development of a heart rate measuring device using fingertip \[C\]∥ 2010 International Conference on Computer and Communication Engineering (ICCCE). Kuala Lumpur: \[s. n.\], 2010: 15.
[11] CHO M C, KIM J Y, CHO S H. A bio-impedance measurement system for portable monitoring of heart rate and pulse wave velocity using small body area \[C\]∥ 2009 IEEE International Symposium on Circuits and Systems, ISCAS. Taipei: IEEE, 2009: 3106-3109.
[12] BANSAL D, KHAN M, SALHAN A K. Real time acquisition and PC to PC wireless transmission of human carotid pulse waveform \[J\]. Computers in Biology and Medicine, 2009, 39(10): 915-920.
[13] GUPTA G S, MUKHOPADHYAY S C, DEVLIN B S, et al. Design of a low-cost physiological parameter measurement and monitoring device \[C\]∥ Instrumentation and Measurement Technology Conference Proceedings. Warsaw: \[s. n.\], 2007: 16.
[14] JUBADI W M, MOHDSAHAK S F A. Heartbeat monitoring alert via SMS \[C\]∥ IEEE Symposium on Industrial Electronics and Applications. Kuala Lumpur: IEEE, 2009: 15.
[15] MALHIS K, MUKHOPADHYAY S C, SCHNEPPERET J, et al. A Zigbee based wearable physiological parameters monitoring system \[J\]. Sensors Journal, IEEE, 2012, 12(3): 423-430.
[16] PARK J, CHO J, NAM T, et al. A unconstrained multi-channel heart rate monitoring system for exercising rehabilitation patients \[C\]∥ 29th Annual International Conference of the IEEE on Engineering in Medicine and Biology Society. Lyon: IEEE, 2007: 3512-3515.
[17] RENEVEY P, VETTER R, KRAUSS J, et al. Wrist-located pulse detection using IR signals, activity and nonlinear artifact cancellation \[C\]∥ Proceedings of the 23rd Annual International Conference of the IEEE on Engineering in Medicine and Biology Society. Istanbul: IEEE, 2001: 3030-3033.
[18] MUKHOPADHYAY S C, GUPTA G S. A physiological parameter monitoring device to care for the elderly \[C\]∥ Sensors, 2008 IEEE. Lecce: IEEE, 2008: 1324-1327.
[19] CIACCIO E J, DRZEWIECKI G M. Tonometric arterial pulse sensor with noise cancellation \[J\]. IEEE Transactions on Biomedical Engineering, 2008, 55(10): 2388-2396.
[20] HAYES M J, SMITH P R. A  new method for pulse oximetry possessing inherent insensitivity to artifact \[J\]. IEEE Transactions on Biomedical Engineering, 2001, 48(4): 452-461.
[21] CIACCIO E J, DRZEWIECKI G M. Array sensor for arterial pulse recording-reduction of motion artifact \[C\]∥ Proceedings of the 1988 14th Annual Northeast Bioengineering Conference. Durham, NH: \[s. n.\], 1988: 66-69.
[22] LEE Y, HAN H, KIM J. Influence of motion artifacts on photoplethysmographic signals for measuring pulse rates \[C\]∥ 2008 International Conference on Control, Automation and Systems. Seoul: \[s. n.\], 2008: 962965.\[23\] 李桥, ROGER G M, 俞梦孙,等.基于信号质量评估和卡尔曼滤波的心率估计算法\[J\].中国医学物理学杂志, 2007, 124(6): 454-457.
LI Qiao, ROGER G M, YU Meng-sun, et al. Heart rate estimation algorithm based on signal quality estimation and Kalman filter \[J\]. Chinese Journal of Medical Physics, 2007, 124(6): 454-457.

[1] 王琴, 方佳如, 曹端喜, 周洁, 苏凯麒, 黎洪波, 王平. 心肌细胞传感器优化设计及其药物分析[J]. 浙江大学学报(工学版), 2016, 50(6): 1214-1220.
[2] 王琴, 方佳如, 曹端喜, 周洁, 苏凯麒, 黎洪波, 王平. 心肌细胞传感器优化设计及其药物分析[J]. 浙江大学学报(工学版), 2015, 49(12): 2432-2438.
[3] 陈婧, 许敏芬, 王立强, 袁波, 段会龙, 唐佳. 用于FICE图像增强效果的客观评价方法[J]. 浙江大学学报(工学版), 2015, 49(10): 2013-2017.
[4] 郑翔,张寅升,黄震震,贾峥,段会龙,赵饮虹,李昊旻. 可扩展的临床决策支持应用集成架构[J]. 浙江大学学报(工学版), 2015, 49(9): 1658-1664.
[5] 何为, 夏灵. 基于掩码的区域增长相位解缠方法[J]. 浙江大学学报(工学版), 2015, 49(4): 792-797.
[6] 李江,赵雅琼,包晔华. 基于混沌和替代数据法的中风病人声音分析[J]. 浙江大学学报(工学版), 2015, 49(1): 36-41.
[7] 何为, 夏灵. 基于掩码的区域增长相位解缠方法[J]. 浙江大学学报(工学版), 2014, 48(11): 1-2.
[8] 杨明雷,丁辉,王晓东,王广志. 呼吸引起的肝脏运动模式分析[J]. 浙江大学学报(工学版), 2014, 48(9): 1710-1720.
[9] 毛贺,陈章位,黄靖,胡科伟. PCR仪温度场热模型的研究与验证[J]. J4, 2013, 47(9): 1619-1624.
[10] 吴栋栋, 张文光, MERCERON Gilles, 罗云. 神经电极-脑组织界面微动环境力学特性仿真[J]. J4, 2013, 47(2): 256-260.
[11] 程功, 王江容, 吴成雄, 胡宁, 周洁, 王平. 细胞生理多参数自动分析仪的
软件设计及算法分析
[J]. J4, 2012, 46(12): 2285-2292.
[12] 吴成雄,蔡华,胡宁,胡朝颖,程功,肖丽丹,余辉,王平. 基于集成芯片的细胞生理多参数自动分析仪[J]. J4, 2012, 46(9): 1715-1721.
[13] 涂岳文, 陈杭, 付秀泉, 李顶立, 黄超, 汤亚伟, 叶树明. 基于心搏聚类的Holter运动伪差段快速识别算法[J]. J4, 2012, 46(6): 1148-1156.
[14] 封洲燕, 王静, 汪洋, 郑晓静. 神经元锋电位信号滤波频率的选择[J]. J4, 2012, 46(2): 351-358.
[15] 王娟,黄忠朝,刘正春. 基于增强的谱分析和奇异值分解的T波交替检测[J]. J4, 2012, 46(1): 177-181.