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浙江大学学报(工学版)
JOURNAL OF ZHEJIANG UNIVERSITY (ENGINEERING SCIENCE)
Mechanical and Electrical Engineering     
Simulation study on magnetic resonance electrical property tomography of human abdominal cancer
LIU Yang, YU Xiao hui, GUO Jian yan
1. School of Electrical Engineering and Automation, Xiamen University of Technology, Xiamen 361024, China;
2. Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute, Houston 77030, USA;
3. School of Opto-Electronic and Communication Engineering, Xiamen University of Technology, Xiamen 361024, China
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Abstract  

The magnetic resonance electrical property tomography (MREPT) method was applied to human abdomen. The birdcage coil was used for radio frequency (RF) transmission and reception. The conductivity and relative permittivity of abdominal tissues were reconstructed based on the RF field measurement. The simulation results conducted on human abdominal model including 10 types of tissues show that the MREPT can detect the 3cm-radius liver cancer tumor and 1cm-radius pancreas tumor located in the central area of tissues. MREPT may fail to detect the small tumors located near the boundary of tissues due to the homogeneous electrical property assumption made in the reconstruction algorithm together with the adopted Laplacian revolution. The size of Laplacian revolution kernel has significant influence on the reconstruction result. When there is no noise, the 3×3×3 Laplacian revolution kernel can achieve the highest accuracy. The best performance can be achieved by 5×5×5 Laplacian revolution kernel with a SNR in the range of 30 to 120.

Published: 28 October 2016
CLC:  TM 15  
  TP 391  
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Cite this article:

LIU Yang, YU Xiao hui, GUO Jian yan. Simulation study on magnetic resonance electrical property tomography of human abdominal cancer. JOURNAL OF ZHEJIANG UNIVERSITY (ENGINEERING SCIENCE), 2016, 50(10): 1959-1964.

URL:

http://www.zjujournals.com/eng/10.3785/j.issn.1008-973X.2016.10.016     OR     http://www.zjujournals.com/eng/Y2016/V50/I10/1959


磁共振电特性成像人体腹腔癌症仿真研究

将磁共振电特性成像(MREPT)方法用于人体腹腔部位,考察该成像方式用于人体腹腔肝癌及胰腺癌诊断的可行性.采用鸟笼线圈同时作为射频发射和接收,基于射频发射场测量值重构人体腹腔内组织的电导率和相对介电率.包含10种组织的人体腹腔模型上的仿真结果表明：在信噪比SNR=30的情况下,MREPT能够检测出位于组织内部半径为3 cm的肝癌肿瘤和半径为1 cm的胰腺癌肿瘤；由于逆问题重构公式中均质电特性的假设及拉普拉斯卷积的共同作用,可能无法检测出位于组织边界处的小体积癌症肿瘤.拉普拉斯卷积核的大小对重构结果的影响很大,在无噪声情况下,3×3×3的卷积核的重构效果最好,但当SNR=30～120时,5×5×5的卷积核是最佳选择.

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