Please wait a minute...
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2014, Vol. 15 Issue (6): 598-600    DOI: 10.1631/jzus.B1400078
Correspondence     
Hypocalcemia: a reversible cause of T wave alternans and heart failure
Yi-chen Yang, Fa-rong Shen, Yuan-qiang Lu
Department of Clinical Medicine, Graduate School, Zhejiang Chinese Medical University, Hangzhou 310053, China; Department of Emergency Medicine, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China
Download:     PDF (0 KB)     
Export: BibTeX | EndNote (RIS)      

Abstract  We have read with great interest the recent article “Cellular mechanism of cardiac alternans: an unresolved chicken or egg problem” by Zang and Xia (2014), published in Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). The authors proposed that both calcium handling and electrical components of cardiac cells could be the cellular mechanism of cardiac alternans, and identifying the main mechanism of cardiac alternans could help to cure targeted patients with heart failure. Here, we present a particular case, which may help you to understand our viewpoint.

Key wordsHypocalcemia      Heart failure      Arrhythmias      Cardiac      Hypoparathyroidism     
CLC:  R541.7+6  
Cite this article:

Yi-chen Yang, Fa-rong Shen, Yuan-qiang Lu. Hypocalcemia: a reversible cause of T wave alternans and heart failure. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2014, 15(6): 598-600.

URL:

http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.B1400078     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2014/V15/I6/598

[1] Na Zhang, Xiao-jie Xie, Jian-an Wang. Multifunctional protein: cardiac ankyrin repeat protein[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2016, 17(5): 333-341.
[2] De-xing Hu, Xian-bao Liu, Wen-chao Song, Jian-an Wang. Roles of SIRT3 in heart failure: from bench to bedside[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2016, 17(11): 821-830.
[3] Hao-jian Dong, Cheng Huang, De-mou Luo, Jing-guang Ye, Jun-qing Yang, Guang Li, Jian-fang Luo, Ying-ling Zhou. Concomitant coronary and renal revascularization improves left ventricular hypertrophy more than coronary stenting alone in patients with ischemic heart and renal disease[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2016, 17(1): 67-75.
[4] Yun-liang Zang, Ling Xia. Cellular mechanism of cardiac alternans: an unresolved chicken or egg problem[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2014, 15(3): 201-211.
[5] He-qing Zhan, Ling Xia, Guo-fa Shou, Yun-liang Zang, Feng Liu, Stuart Crozier. Fibroblast proliferation alters cardiac excitation conduction and contraction: a computational study[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2014, 15(3): 225-242.
[6] Geng Qian, Chen Wu, Yun-dai Chen, Chen-chen Tu, Jin-wen Wang, Yong-an Qian. Predictive factors of cardiac rupture in patients with ST-elevation myocardial infarction[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2014, 15(12): 1048-1054.
[7] Jing Wang, Tao Guo. Metabolic remodeling in chronic heart failure[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2013, 14(8): 688-695.
[8] Hai-ying Xu, Yi-zhou Xu, Feng Ling, Zhong Yu, Jun Yang, Xu Duan, Bei Wang, Jin-yu Huang. Application of CRT-D in a Marfan syndrome patient with chronic heart failure accompanied by ventricular tachycardia and ventricular fibrillation[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2013, 14(8): 759-762.
[9] Xuan Huang, Shu Lei, Mei-fei Zhu, Rong-lin Jiang, Li-quan Huang, Guo-lian Xia, Yi-hui Zhi. Levosimendan versus dobutamine in critically ill patients: a meta-analysis of randomized controlled trials[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2013, 14(5): 400-415.
[10] Dong-dong Deng, Ying-lan Gong, Guo-fa Shou, Pei-feng Jiao, Heng-gui Zhang, Xue-song Ye, Ling Xia. Simulation of biatrial conduction via different pathways during sinus rhythm with a detailed human atrial model[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2012, 13(9): 676-694.
[11] Ze-wei Tao, Long-gui Li, Zhao-hua Geng, Tao Dang, Shan-jun Zhu. Growth factors induce the improved cardiac remodeling in autologous mesenchymal stem cell-implanted failing rat hearts[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2010, 11(4): 238-248.
[12] He LI, Xiao-qing MA, Fan YE, Jing ZHANG, Xin ZHOU, Zhi-hong WANG, Yu-ming LI, Guo-yuan ZHANG. Expressions of cardiac sympathetic norepinephrine transporter and β1-adrenergic receptor decreased in aged rats[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2009, 10(3): 203-210.
[13] TAO Ze-wei, LI Long-gui. Cell therapy in congestive heart failure[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2007, 8(9): 647-660.
[14] LI Nan, WANG Jian-an. Brain natriuretic peptide: A potential indicator of cardiomyogenesis after autologous mesenchymal stem cell transplantation?[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2006, 7(9 ): 16-.
[15] Jiang Qing-Jun, Xu Geng, Mao Fei-Fei, Zhu You-Fa. Effects of combination of irbesartan and perindopril on calcineurin expression and sarcoplasmic reticulum Ca2+-ATPase activity in rat cardiac pressure-overload hypertrophy[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2006, 7(3 ): 10-.