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ZJUS-B
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2008, Vol. 9 Issue (4): 324-328    DOI: 10.1631/jzus.B0710359
Biomedicine     
Changes of tear film and tear secretion after phacoemulsification in diabetic patients
Xi LIU, Yang-shun GU, Ye-sheng XU
Ophthalmology Center, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China
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Abstract  Objective: To evaluate tear film stability and tear secretion in patients with diabetes after phacoemulsification. Methods: Twenty-five diabetic cataract patients and 20 age-matched non-diabetic cataract patients as control underwent phacoemulsification. Tear film break-up time (TFBUT), Schirmer I test (SIT), corneal fluorescein staining, and dry eye symptoms were measured pre- and postoperatively. Results: Diabetics had a decreased preoperative TFBUT and SIT. TFBUT was reduced on Day 1 and recovered on Day 180 postoperatively in both groups. SIT was increased after phacoemulsification, but returned to preoperative levels by Day 180 in non-diabetics, whereas it was lower than preoperative level in diabetics. Positive corneal fluorescein staining was elevated in both groups, and returned to preoperative levels only in controls. Dry eye symptoms were similar to fluorescein staining in both groups. Conclusion: Tear secretion was reduced in diabetic cataract patients after phacoemulsification, which worsened dry eye symptoms and predisposed those patients to ocular damage.

Key words： Phacoemulsification      Diabetes      Cataract      Tear     
Received: 04 July 2007     
CLC:  R776  
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Ye-sheng XU
Xi LIU
Yang-shun GU
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Xi LIU, Yang-shun GU, Ye-sheng XU. Changes of tear film and tear secretion after phacoemulsification in diabetic patients. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2008, 9(4): 324-328.

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http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.B0710359     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2008/V9/I4/324

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