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ZJUS-B
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2006, Vol. 7 Issue (9 ): 15-    DOI: 10.1631/jzus.2006.B0763
    
Basal or bolus dose, which is the key factor in CSII?
YANG Nai-long, XUE Bing, LIN Peng
Department of Endocrinology, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China; Department of Endocrinology, Shenyang General Hospital, Shenyang 110016, China
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Abstract  Objective: To observe the value of HbA1c level evaluating the total daily basal insulin dose by continuous subcutaneous insulin infusion (CSII) in 268 patients with type 2 diabetes mellitus. Methods: 5-point capillary blood glucose was monitored in pre- and post-CSII and the insulin dose which could stabilize blood glucose was defined as the total daily dose of insulin, including basal and bolus total dose. Correlation between HbA1c level and total daily dose of insulin in patients with type 2 diabetes mellitus was analyzed. Correlation between HbA1c level and 5-point capillary blood glucose was also analyzed. Results: Obvious correlation was observed between HbA1c level and the basal total daily dose of insulin if HbA1c was more than 9.3% (r=0.635, P<0.05). The average of 5-point capillary blood glucose was best correlated with HbA1c and fasting blood glucose next best. Conclusion: HbA1c level can forecast basal total daily dose of insulin in CSII.

Key words： Type 2 diabetes mellitus      HbA1c      Basal total daily dose of insulin      CSII (continuous subcutaneous insulin infusion)     
Received: 18 June 2006     
CLC:  R58  
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YANG Nai-long
XUE Bing
LIN Peng
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YANG Nai-long, XUE Bing, LIN Peng. Basal or bolus dose, which is the key factor in CSII?. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2006, 7(9 ): 15-.

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http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.2006.B0763     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2006/V7/I9 /15

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