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ZJUS-B
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2009, Vol. 10 Issue (5): 341-347    DOI: 10.1631/jzus.B0820310
Biomedicine     
Determinants of lexical access in pure-anomic recovery: a longitudinal study
Xiao ZHOU, Hui LIANG, Ming-wei XU, Ben-yan LUO
Neuropsychology Laboratory, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China
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Abstract  Many studies involving lexical access in picture-naming tasks have been undertaken at a point in time, mainly focusing on age of acquisition (AoA). To identify the real determinates of lexical access in recovery and their traces in the brain, we carried out a longitudinal study on a Chinese pure anomic patient using multiple logistic regression analysis. We found that AoA played an important role in early recovery but not in total recovery, whereas familiarity was significant in the whole process. From a new dynamic point of view, our results indicate that AoA and familiarity are the main determinants of lexical access in anomia recovery. We suggest that the changing effects of AoA during recovery may be related to the pathologic process; AoA and familiarity should be taken into account in constructing materials to assess and treat anomic patients.

Key words： Object naming      Age of acquisition      Anomia      Therapy     
Received: 28 September 2008     
CLC:  R74  
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Xiao ZHOU
Hui LIANG
Ming-wei XU
Ben-yan LUO
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Xiao ZHOU, Hui LIANG, Ming-wei XU, Ben-yan LUO. Determinants of lexical access in pure-anomic recovery: a longitudinal study. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2009, 10(5): 341-347.

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http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.B0820310     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2009/V10/I5/341

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