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| Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach |
| Wen-hua Ruan, Mei-li Huang, Xiao-lei He, Feng Zhang, Hai-biao Tao |
| Department of Stomatology, Children's Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China; Department of Otolaryngology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China; Department of Stomatology, Lishui People's Hospital, Lishui 323000, China |
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Abstract Objective: To evaluate the pharmacological effects of traditional Chinese medicine, bear bile capsule and Huangqi granule, on recurrent parotitis in children. Methods: In this prospective, controlled, and randomized study, a total of 151 young children were divided into three groups: Group A included massaging the children’s parotid region and melting vitamin C in their mouth daily; Group B included swallowing bear bile capsule and Huangqi granule daily; and Group C included massages and vitamin C as prescribed in Group A, and traditional Chinese medicine as prescribed in Group B. Children were treated individually for one month and then a follow-up study was conducted for 1 to 3.5 years. Analysis of variance (ANOVA) and Ridit analysis were employed for statistical analysis. Results: The recurrence rate decreased in every group, but was significantly more in Groups B and C when compared to Group A. The recurrences significantly decreased (P<0.01) in Group B and their recovery rate was as high as 63%, significantly better than those of the other groups (P<0.01). Conclusions: Huangqi and bear bile could be a novel clinical approach for treating recurrent parotitis in children.
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Received: 10 March 2012
Published: 06 March 2013
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