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浙江大学学报（农业与生命科学版）
浙江大学学报(农业与生命科学版)  2012, Vol. 38 Issue (4): 524-528    DOI: 10.3785/j.issn.1008-9209.2012.04.023
食品科学     
萼状粒毛盘菌多糖的生物活性
宋世玉1， 袁如月1， 孙柘1， 王平1， 蔡敬民2， 叶明1
1.合肥工业大学 生物与食品工程学院，安徽 合肥 230009；2.合肥学院 生物与环境工程系，安徽 合肥 230022
Biological activity of polysaccharides produced by Lachnum calyculiforme
SONG Shiyu1, YUAN Ruyue1, SUN Zhe1, WANG Ping1, CAI JingMin2, YE Ming1
1College of Biotechnology and Food Engineering, Hefei University of Technology, Hefei 230009, China; 2Department of Biological and Environmental Engineering, Hefei University, Hefei 230022, China
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摘要： 研究萼状粒毛盘菌YM-262胞内、胞外多糖对亚硝基的清除作用、对丙二醛生成的抑制作用、对线粒体的保护作用和抗炎作用。结果表明：胞内、胞外多糖质量浓度为1.2 g·L-1时对亚硝酸盐的清除率可达最大，分别为63.21%和52.43%；胞内、胞外多糖均能显著抑制肝匀浆在自氧化和诱导氧化中丙二醛的生成，抑制率分别为32.81%和36.46%；此外，YM262多糖可抑制·OH所致的氧化损伤，减轻线粒体膜肿胀度，且胞内多糖的抑制率大于胞外多糖；胞内多糖和胞外多糖均可显著抑制二甲苯所致的小鼠耳廓肿胀，减少左右耳质量差，且具有一定的剂量效应关系，胞内多糖和胞外多糖剂量为400 mg·kg-1时，抑制率分别为56.68%和51.87%。
Abstract: The effects of intracellular polysaccharide (LIP) and extracellular polysaccharide (LEP) from Lachnum calyculiforme  YM-262 on the elimination of nitrite radicals，the inhibition of MDA formation, the protective action of mitochondria, and the antiinflammation were studied. The results indicated that the clearance rates of nitrite could reach 63.21% and 52.43% at 1.2 g·L-1 of LIP and LEP, respectively. LIP and LEP could significantly inhibit the amount of malondialdehyde which was produced by liver homogenate in the selfinduced oxidation and the induced oxidation. The inhibition rate of malondialdehyde were 32.81% and 36.46% at 1.2 g·L-1 of LIP and LEP,  respectively In addition, polysaccharides from L. calyculiforme  YM-262 could inhibit the oxidative damage made by ·OH and reduce the swelling degree of mitochondrial membrane, and the LIP’s inhibitory rate was higher than the LEP’s- LIP and LEP could significantly inhibit the auricle tumefaction of mice and reduce the mass difference between the right and the left ear, which had certain doseeffect relations The antiinflammatory action could reach 5668% and 51.87% with 400 mg·kg-1 of LIP and LEP, respectively.
出版日期: 2012-07-25
CLC:  TQ 929.2  
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宋世玉1
袁如月1
孙柘1
王平1
蔡敬民2
叶明1

引用本文:

宋世玉1， 袁如月1， 孙柘1， 王平1， 蔡敬民2， 叶明1. 萼状粒毛盘菌多糖的生物活性[J]. 浙江大学学报(农业与生命科学版), 2012, 38(4): 524-528.

SONG Shiyu1, YUAN Ruyue1, SUN Zhe1, WANG Ping1, CAI JingMin2, YE Ming1. Biological activity of polysaccharides produced by Lachnum calyculiforme. , 2012, 38(4): 524-528.

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http://www.zjujournals.com/agr/CN/10.3785/j.issn.1008-9209.2012.04.023    或    http://www.zjujournals.com/agr/CN/Y2012/V38/I4/524

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