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Three-dimensional organ modeling based on deformable surfaces applied to radio-oncology |
Gloria Bueno*,1, Oscar Déniz1, Jesús Salido1, Carmen Carrascosa2, José M. Delgado3 |
1 Grupo de Visión y Sistemas Inteligentes, Universidad de Castilla-La Mancha, E.T.S. Ingenieros Industriales Avda. Camilo José Cela, 3. 13071 Ciudad Real, Spain
2 Hospital General de Ciudad Real, Tomelloso s/n. 13005 Ciudad Real, Spain
3 Instituto Oncológico (Grupo IMO) Modesto Lafuente, 14, 28010 Madrid, Spain
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Abstract This paper describes a method based on an energy minimizing deformable model applied to the 3D biomechanical modeling of a set of organs considered as regions of interest (ROI) for radiotherapy. The initial model consists of a quadratic surface that is deformed to the exact contour of the ROI by means of the physical properties of a mass-spring system. The exact contour of each ROI is first obtained using a geodesic active contour model. The ROI is then parameterized by the vibration modes resulting from the deformation process. Once each structure has been defined, the method provides a 3D global model including the whole set of ROIs. This model allows one to describe statistically the most significant variations among its structures. Statistical ROI variations among a set of patients or through time can be analyzed. Experimental results are presented using the pelvic zone to simulate anatomical variations among structures and its application in radiotherapy treatment planning.
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Received: 04 July 2009
Published: 02 June 2010
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Fund: Project partially supported by the VI FP and VII FP of the European Commission through MAESTRO and ENVISION
projects (Nos. IP CE503564 and SP CE241851) and Spanish Junta de Comunidades de Castilla–La Mancha (Nos. PBC06-
0019 and PI-2006/01.1) |
Three-dimensional organ modeling based on deformable surfaces applied to radio-oncology
This paper describes a method based on an energy minimizing deformable model applied to the 3D biomechanical modeling of a set of organs considered as regions of interest (ROI) for radiotherapy. The initial model consists of a quadratic surface that is deformed to the exact contour of the ROI by means of the physical properties of a mass-spring system. The exact contour of each ROI is first obtained using a geodesic active contour model. The ROI is then parameterized by the vibration modes resulting from the deformation process. Once each structure has been defined, the method provides a 3D global model including the whole set of ROIs. This model allows one to describe statistically the most significant variations among its structures. Statistical ROI variations among a set of patients or through time can be analyzed. Experimental results are presented using the pelvic zone to simulate anatomical variations among structures and its application in radiotherapy treatment planning.
关键词:
3D biomechanical organ modeling,
Energy minimizing deformable model,
Finite element model,
Geodesic active contour,
Radiotherapy treatment planning
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