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ZJUS-B
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2008, Vol. 9 Issue (9): 734-738    DOI: 10.1631/jzus.B0820099
Biomedicine     
Modeling of human colonic blood flow for a novel artificial anal sphincter system
Peng ZAN, Guo-zheng YAN, Hua LIU
School of Electronics, Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
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Abstract  A novel artificial anal sphincter system has been developed to simulate the normal physiology of the human anorectum. With the goal of engineering a safe and reliable device, the model of human colonic blood flow has been built and the relationship between the colonic blood flow rate and the operating occlusion pressure of the anorectum is achieved. The tissue ischemia is analyzed based on constitutive relations for human anorectum. The results suggest that at the planned operating occlusion pressure of less than 4 kPa the artificial anal sphincter should not risk the vascularity of the human colon.

Key words： Incontinence      Artificial anal sphincter      Colonic blood flow      Tissue ischemia     
Received: 28 March 2008     
CLC:  R57  
  TN99  
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Peng ZAN
Guo-zheng YAN
Hua LIU
Cite this article:

Peng ZAN, Guo-zheng YAN, Hua LIU. Modeling of human colonic blood flow for a novel artificial anal sphincter system. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2008, 9(9): 734-738.

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http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.B0820099     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2008/V9/I9/734

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[2] Peng Zan, Bang-hua Yang, Yong Shao, Guo-zheng Yan, Hua Liu. Electromagnetic effects on the biological tissue surrounding a transcutaneous transformer for an artificial anal sphincter system[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2010, 11(12): 931-936.