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Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2012, Vol. 13 Issue (8): 624-630    DOI: 10.1631/jzus.B1201002
Articles     
Value of a new post-procedural intravascular ultrasound score in predicting target vessel revascularization after coronary drug-eluting stents implantation
Kai Xu, Ya-ling Han, Quan-min Jing, Shou-li Wang, Ying-yan Ma, Xiao-zeng Wang, Geng Wang, Zu-lu Wang
Department of Cardiology, Shenyang Northern Hospital, Shenyang 110016, China
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Abstract  Objective: There is no simple or feasible post-procedural intravascular ultrasound (IVUS) score to predict major adverse cardiac events (MACE) in patients undergoing drug-eluting stents (DES) implantation. The aim of this study is to validate a new IVUS score for predicting MACE. Methods: A total of 295 patients (with 322 lesions) were enrolled. IVUS score was calculated in each lesion based on five IVUS morphological characteristics: inflow/outflow disease, malapposition, underexpansion, tissue protrusion, and edge dissection (iMUTE score). We assigned two points to an underexpansion and one point for each presence of other factors. Patients were divided into low score (iMUTE score<2, n=137) and high score (iMUTE score≥2, n=158) groups. Results: At one year follow-up, a trend was seen in favor of the low iMUTE score group in MACE (3.65% vs. 10.10%; P=0.052), and there was more target vessel revascularization (TVR) in the high iMUTE score group compared with low score group (6.96% vs. 1.46%; P=0.044). Low iMUTE score was an independent predictor of freedom from TVR at one year (adjusted hazard ratio (HR) 0.5, 95% confidence interval (CI) 0.10.8; P=0.02). Conclusions: Post-procedural IVUS iMUTE scoring was simple and feasible in clinical practice, and can provide independent prognostic value for TVR in patients undergoing DES implantation.

Key wordsIntravascular ultrasound      Drug eluting stents      Scoring schemes      percutaneous coronary intervention     
Received: 08 June 2012      Published: 01 August 2012
CLC:  R541.4  
Cite this article:

Kai Xu, Ya-ling Han, Quan-min Jing, Shou-li Wang, Ying-yan Ma, Xiao-zeng Wang, Geng Wang, Zu-lu Wang. Value of a new post-procedural intravascular ultrasound score in predicting target vessel revascularization after coronary drug-eluting stents implantation. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2012, 13(8): 624-630.

URL:

http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.B1201002     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2012/V13/I8/624

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