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ZJUS-B
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2012, Vol. 13 Issue (8): 638-644    DOI: 10.1631/jzus.B1201005
Articles     
Renal insufficiency is an independent predictor of in-hospital mortality for patients with acute myocardial infarction receiving primary percutaneous coronary intervention
Jian-ping Li, Mohetaboer Momin, Yong Huo, Chun-yan Wang, Yan Zhang, Yan-jun Gong, Zhao-ping Liu, Xin-gang Wang, Bo Zheng
Department of Cardiology, Peking University First Hospital, Peking University, Beijing 100043, China
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Abstract  Objective: To investigate the relationship between renal function and clinical outcomes among patients with acute ST-segment elevation myocardial infarction (ASTEMI), who were treated with emergency percutaneous coronary intervention (PCI). Methods: 420 patients hospitalized in Peking University First Hospital, diagnosed with ASTEMI treated with emergency (PCI) from January 2001 to June 2011 were enrolled in this study. Estimated glomerular filtration rate (eGFR) was used as a measure of renal function. We compared the clinical parameters and outcomes between ASTEMI patients combined renal insufficiency and the patients with normal renal function. Results: There was a significant increase in the concentrations of fibrinogen and D-Dimer (P<0.05) and a much higher morbidity of diabetes mellitus in the group of patients with chronic kidney disease (CKD; eGFR<60 ml/(min·1.73 m2)) (P<0.01). CKD (eGFR<60 ml/(min·1.73 m2)) was an independent predictor of in-hospital mortality for patients hospitalized with ASTEMI receiving PCI therapy rapidly (P=0.032, odds ratio (OR) 4.159, 95% confidence interval (CI) 1.127–15.346). Conclusions: Renal insufficiency is an independent predictor of in-hospital mortality for patients hospitalized with ASTEMI treated with primary PCI.

Key words： Acute myocardial infarction (AMI)      Percutaneous coronary intervention (PCI)      Renal function      Estimated glomerular filtration rate (eGFR)      Mortality     
Received: 18 June 2012      Published: 01 August 2012
CLC:  R453.9  
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Articles by authors
Jian-ping Li
Bo Zheng
Mohetaboer Momin
Yong Huo
Chun-yan Wang
Yan Zhang
Yan-jun Gong
Zhao-ping Liu
Xin-gang Wang
Cite this article:

Jian-ping Li, Mohetaboer Momin, Yong Huo, Chun-yan Wang, Yan Zhang, Yan-jun Gong, Zhao-ping Liu, Xin-gang Wang, Bo Zheng. Renal insufficiency is an independent predictor of in-hospital mortality for patients with acute myocardial infarction receiving primary percutaneous coronary intervention. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2012, 13(8): 638-644.

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http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.B1201005     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2012/V13/I8/638

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