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ZJUS-B
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2006, Vol. 7 Issue (1 ): 10-    DOI: 10.1631/jzus.2006.B0056
    
Effects of two medicinal plants Psidium guajava L. (Myrtaceae) and Diospyros mespiliformis L. (Ebenaceae) leaf extracts on rat skeletal muscle cells in primary culture
Belemtougri R.G., Constantin B., Cognard C., Raymond G., Sawadogo L.
Laboratory of Physiological Animal, University of Ouagadougou BP 7021, Burkina Faso; Institute of Physiology & Biology Cell, University of Poitiers, France
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Abstract  Crude decoction, aqueous and ethanolic extracts of two medicinal plants (Psidium guajava and Diospyros mespiliformis), widely used in the central plateau of Burkina Faso to treat many diseases were evaluated for their antagonistic effects on caffeine induced calcium release from sarcoplasmic reticulum of rat skeletal muscle cells. These different extracts showed a decrease of caffeine induced calcium release in a dose dependent manner. Comparison of the results showed that Psidium guajava leaf extracts are more active than extracts of Diospyros mespiliformis and that crude decoctions show better inhibitory activity. The observed results could explaine their use as antihypertensive and antidiarrhoeal agents in traditional medicine, by inhibiting intracellular calcium release.

Key words： Psidium guajava      Diospyros mespiliformis      Myrtaceae      Ebenaceae      Medicinal plants      Intracellular calcium      Sarcoplasmic reticulum      Caffeine     
Received: 04 October 2005     
CLC:  Q958.12+2.5  
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Belemtougri R.G.
Constantin B.
Cognard C.
Raymond G.
Sawadogo L.
Cite this article:

Belemtougri R.G., Constantin B., Cognard C., Raymond G., Sawadogo L.. Effects of two medicinal plants Psidium guajava L. (Myrtaceae) and Diospyros mespiliformis L. (Ebenaceae) leaf extracts on rat skeletal muscle cells in primary culture. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2006, 7(1 ): 10-.

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http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.2006.B0056     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2006/V7/I1 /10

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