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ZJUS-A
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering)  2002, Vol. 3 Issue (2): 243-246    DOI: 10.1631/jzus.2002.0243
Biotechnology & Life Sciences     
Study of sEGF level in chronic atrophic gastritis with either Chinese traditional medicine or western medicine
SI Jian-min, SUN Lei-min, DAI Nin, QIAO Qiao, ZHOU Heng-de, ZHU Shu-dong
Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China; First Affiliated Hospital, Zhejiang Chinese Traditional Medical University, Hangzhou 310006, China
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Abstract  This study was aimed to investigate the level of sEGF in CAG with different therapies of either Chinese traditional medicine or western medicine. Patients were divided into spleen-reinforcing I, spleen-reinforcing II, dampness-resolving and western medicine group by Differentiation Syndrome. Healthy volunteers acted as controls. The sEGF was investigated before and after treatment. The level of sEGF in CAG was higher than that in control group (P<0.01). In patients of spleen-reinforcing I group and spleen-reinforcing II group, the symptoms and pathological manifestations were improved dramatically (P<0.01) and sEGF dropped markedly after treatment (P<0.01 and P<0.05).The level of sEGF in the dampness-resolving group increased after treatment (P<0.05). But the level of sEGF in the western-medicine group dropped a little after treatment (P>0.05). The inflammation of gastric mucosa may cause the elevation of sEGF in CAG reflectively. After being effectively treated with Chinese traditional medicine, the symptoms of CAG improved simultaneously with the return of sEGF. SEGF is a sensitive index to prognosis of CAG.

Key words： Epidermal growth factor (EGF)      Chronic atrophic gastritis (CAG)      Chinese traditional medicine     
Received: 29 March 2001     
CLC:  R573.3  
  R975.1  
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SUN Lei-min
SI Jian-min
DAI Nin
QIAO Qiao
ZHOU Heng-de
ZHU Shu-dong
Cite this article:

SI Jian-min, SUN Lei-min, DAI Nin, QIAO Qiao, ZHOU Heng-de, ZHU Shu-dong. Study of sEGF level in chronic atrophic gastritis with either Chinese traditional medicine or western medicine. Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2002, 3(2): 243-246.

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http://www.zjujournals.com/xueshu/zjus-a/10.1631/jzus.2002.0243     OR     http://www.zjujournals.com/xueshu/zjus-a/Y2002/V3/I2/243

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