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ZJUS-A
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering)  2003, Vol. 4 Issue (6): 745-748    DOI: 10.1631/jzus.2003.0745
Medicine     
Ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation
WANG Jian-an, SUN Yong, HE Hong
Sir Run Run Shaw Hospital, Clinical Research Institute, Zhejiang University, Hangzhou 310016, China
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Abstract  Objective: to evaluate the efficacy and safety of ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation. Methods: The study population consisted of 9 patients with 5 males and 4 females enrolled consecutively who had idiopathic paroxysmal atrial fibrillation (AF). The ultrasound balloon was positioned through a special sheath to the orifice of the target vein by a transseptal procedure. The balloon was inflated with contrast-mixed saline (contrast: saline = 1:4) whose volume was decided by the diameter of the target pulmonary vein. The ablation energy was usually set up at 35 to 40 watts with temperature controlled at 60°C. The duration of each ablation was about 120 seconds which was repeated not over 10 times. Results: The average duration of the total procedure was 132±68 min for our patients. The average fluoroscopy time was 33±17 min. With a mean follow-up of 16±8 months after the procedure, AF was completely eliminated in 4 patients without antiarrhythmic drugs. The episodes of atrial fibrillation were eliminated in 2 patients with low dosage of oral amiodarone (0.1, once daily) which was ineffective before the procedure. The frequency of episodes was similar to that before the procedure in 3 patients. There were no complications such as hemopericardium, air embolism and stenosis of the pulmonary veins by angiography, related to the procedure. Conclusion: Ultrasound ablation of the pulmonary veins is a new approach to treat paroxysmal atrial fibrillation. Before we determined its value, we need to do more researches with bigger sample, randomization and comparison design.

Key words： Ultrasound ablation      Paroxysmal atrial fibrillation      Pulminary veins     
Received: 03 March 2003     
CLC:  R540  
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WANG Jian-an
SUN Yong
HE Hong
Cite this article:

WANG Jian-an, SUN Yong, HE Hong. Ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation. Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2003, 4(6): 745-748.

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http://www.zjujournals.com/xueshu/zjus-a/10.1631/jzus.2003.0745     OR     http://www.zjujournals.com/xueshu/zjus-a/Y2003/V4/I6/745

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