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ZJUS-A
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering)  2002, Vol. 3 Issue (5): 632-635    DOI: 10.1631/jzus.2002.0632
Biotechnology & Life Sciences     
Value of the adenosine test for diagnosis of dual AV nodal physiology in patients with AV nodal reentrant tachycardia
ZHOU Bin-quan, HU Shen-jiang, LU Duan, WANG Jian-an
Dept. of Cardiology, Sir Run Run Shaw Hospital, Medical College, ZheJiang University, Hangzhou 310016, China; Dept. of Cardiology, First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou 310003, China
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Abstract  Objectives: This study was aimed at assessing the value of the adenosine test for noninvasive diagnosis of dual AV nodal physiology (DAVNP) in patients with AV nodal reentrant tachycardia (AVNRT). Methods: 53 patients with paroxysmal supraventricular tachycardia (PSVT) were given incremental doses of adenosine intravenously during sinus rhythm before electrophysiological study. The adenosine test was repeated on a subset of 18 patients with AVNRT after radiofrequency catheter ablation. Results: Sudden increments of PR interval of more than 60 msec between two consecutive beats were observed in 26 (83.9%) of 31 patients with typical AVNRT and 2 (9.1%) of 22 patients with AVRT and AT (P<0.01). The maximal PR increment between 2 consecutive beats in the AVNRT group(105±45ms) was significantly greater than that in the AVRT and AT group (20±13ms) (P<0.01).In postablation adenosine test, DAVNP was eliminated in all 8 patients who underwent slow pathway abolition that EPS showed the slow pathway disappeared and 4 of 10 patients who underwent slow pathway modification that EPS showed the slow pathway persisted. Six of 10 patients who exhibited persistent duality showed a marked reduction in the number of beats conducted in the slow pathway after adenosine injection (P<0.01). Conclusions: Administration of adenosine during sinus rhythm may be a useful bedside test for diagnosis of DAVNP in high percentage of patients with typical AVNRT and additionally for evaluating the effects of radiofrequency ablation.

Key words： Adenosine      Dual AV nodal      Electrophysiology      Tachycardia      AV nodal reentrant     
Received: 05 December 2001     
CLC:  R540.4  
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ZHOU Bin-quan
HU Shen-jiang
LU Duan
WANG Jian-an
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ZHOU Bin-quan, HU Shen-jiang, LU Duan, WANG Jian-an. Value of the adenosine test for diagnosis of dual AV nodal physiology in patients with AV nodal reentrant tachycardia. Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2002, 3(5): 632-635.

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http://www.zjujournals.com/xueshu/zjus-a/10.1631/jzus.2002.0632     OR     http://www.zjujournals.com/xueshu/zjus-a/Y2002/V3/I5/632

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