The review focused on recent advances and innovations on the use of maize varietal resistance and plant materials in the control of Sitophilus zeamaisMotschulsky. New biological techniques for assessing the resistance of varieties of maize to postharvest infestation by S. zeamias were highlighted. It was suggested that routine analysis of plant species is particularly important to cope with the problem of resistance to synthetic insecticides in weevil control. So the paper also revealed the important technical guidelines and scoring system for testing plant materials for insecticidal activity. Effective postharvest insect pest management strategy should form part of the overall crop husbandry for preserving the quality of the produce. Use of resistant varieties is the best approach to overcoming the problems of synthetic insecticides in weevil control. However, breeding maize crop to improve resistance against the maize weevil is associated with some technical limitations. These limitations include lack of inter-specific cross-compatibility, methodological constraints, biotic variation, undesirable genetic linkages, and limited knowledge of genetic bases of resistance. During screening of plant species for insecticidal activities, an untreated control and a reference insecticide whose efficacy in different agro-ecological zones is known should be designated and the plant material should be tested at economically justified doses. The review presented some advances and innovations on the use of maize resistance (including new formulae and scoring systems) in the control of weevil infestation and addressed maize quality and safety after pest-control process. Findings will enhance reorientation of research focus and provide new impetus for the protection of stored maize against S. zeamais attack.