Please wait a minute...
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2017, Vol. 18 Issue (5): 449-452    DOI: 10.1631/jzus.B1600411
Correspondences     
Recurrence of non-cardiogenic pulmonary edema and sustained hypotension shock in cystic pheochromocytoma
Jin Dai, Shen-jie Chen, Bing-sheng Yang, Shu-min Lü, Min Zhu, Yi-fei Xu, Jie Chen, Hong-wen Cai, Wei Mao
Department of Cardiology, Zhejiang Provincial Hospital of Traditional Chinese Medicine, Hangzhou 310006, China; Department of Cardiology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China
Download:   PDF(0KB)
Export: BibTeX | EndNote (RIS)      

Abstract  Pheochromocytoma is a rare neuroendocrine tumor which derives from chromaffin cells of the adrenal gland or relevant to sympathetic nerves and ganglia. The clinical features of pheochromocytoma are various. Paroxysmal episodes of serious hypertension, headache, palpitation, and diaphoresis are the typical manifestations (Bravo, 2004). Hypotension shock, pulmonary edema, and acute coronary syndrome induced by pheochromocytoma are uncommon (Malindretos et al., 2008; Batisse-Lignier et al., 2015). In this study, we present a rare case of cystic pheochromocytoma causing recurrent hypotension shock, non-cardiogenic pulmonary edema, and acute coronary syndrome, and the possible mechanisms are discussed.

Key wordsPheochromocytoma      Non-cardiogenic pulmonary edema      Sustained hypotension      Acute coronary syndrome     
Received: 09 September 2016      Published: 04 May 2017
CLC:  R736.6  
Cite this article:

Jin Dai, Shen-jie Chen, Bing-sheng Yang, Shu-min Lü, Min Zhu, Yi-fei Xu, Jie Chen, Hong-wen Cai, Wei Mao. Recurrence of non-cardiogenic pulmonary edema and sustained hypotension shock in cystic pheochromocytoma. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2017, 18(5): 449-452.

URL:

http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.B1600411     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2017/V18/I5/449


囊性嗜铬细胞瘤复发非心源性肺水肿和持续性低血压休克

概要:本文介绍一例以胸痛、呼吸困难为主要表现,反复发生非心源性肺水肿、持续性低血压和急性冠脉综合征的囊性嗜铬细胞瘤患者。囊性嗜铬细胞瘤合并多种严重并发症临床上少有报道,容易误诊和漏诊。对于出现肺水肿、持续性低血压和急性冠脉综合征等严重体征,临床诊断又不明确的患者,需要考虑嗜铬细胞瘤的可能。

关键词: 囊性嗜铬细胞瘤,  非心源性肺水肿,  持续性低血压,  急性冠脉综合征 
[1]   Batisse-Lignier, M., Pereira, B., Motreff, P., et al., 2015. Acute and chronic pheochromocytoma-induced cardiomyopathies: different prognoses? A systematic analytical review. Medicine (Baltimore), 94(50):e2198.
doi: 10.1097/MD.0000000000002198
[2]   Bravo, E.L., 2004. Pheochromocytoma: current perspectives in the pathogenesis, diagnosis, and management. Arq. Bras. Endocrinol. Metabol., 48(5):746-750.
doi: 10.1590/S0004-27302004000500021
[3]   Dahia, P.L., 2006. Evolving concepts in pheochromocytoma and paraganglioma. Curr. Opin. Oncol., 18(1):1-8.
doi: 10.1097/01.cco.0000198017.45982.06
[4]   Eschen, O., Frøbert, O., Jensen, V., et al., 2007. Pheochromocytoma, a rare cause of acute cardiogenic shock. Clin. Res. Cardiol., 96(4):232-235.
doi: 10.1007/s00392-007-0496-x
[5]   Giavarini, A., Chedid, A., Bobrie, G., et al., 2013. Acute catecholamine cardiomyopathy in patients with phaeochromocytoma or functional paraganglioma. Heart, 99(19): 1438-1444.
doi: 10.1136/heartjnl-2013-304073
[6]   Grasselli, G., Foti, G., Patroniti, N., et al., 2008. Extracorporeal cardiopulmonary support for cardiogenic shock caused by pheochromocytoma: a case report and literature review. Anesthesiology, 108(5):959-962.
doi: 10.1097/ALN.0b013e31816c8a78
[7]   Kopetschke, R., Slisko, M., Kilisli, A., et al., 2009. Frequent incidental discovery of phaeochromocytoma: data from a German cohort of 201 phaeochromocytoma. Eur. J. Endocrinol., 161(2):355-361.
doi: 10.1530/EJE-09-0384
[8]   Li, S.J., Wang, T., Wang, L., et al., 2016. Ventricular tachycardia and resembling acute coronary syndrome during pheochromocytoma crisis: a case report. Medicine (Baltimore), 95(14):e3297.
doi: 10.1097/MD.0000000000003297
[9]   Malindretos, P.M., Sarafidis, P.A., Geropoulou, E.Z., et al., 2008. Sustained hypotension complicating an extra-adrenal pheochromocytoma. Am. J. Hypertens., 21(7): 840-842.
doi: 10.1038/ajh.2008.179
[10]   Omura, M., Saito, J., Yamaguchi, K., et al., 2004. Prospective study on the prevalence of secondary hypertension among hypertensive patients visiting a general outpatient clinic in Japan. Hypertens. Res., 27(3):193-202.
doi: 10.1291/hypres.27.193
[11]   Park, M., Hryniewicz, K., Setaro, J.F., 2009. Pheochromocytoma presenting with myocardial infarction, cardiomyopathy, renal failure, pulmonary hemorrhage, and cyclic hypotension: case report and review of unusual presentations of pheochromocytoma. J. Clin. Hypertens. (Greenwich), 11(2):74-80.
doi: 10.1111/j.1751-7176.2009.00073.x
[12]   Prejbisz, A., Lenders, J.W., Eisenhofer, G., et al., 2011. Cardiovascular manifestations of phaeochromocytoma. J. Hypertens., 29(11):2049-2060.
doi: 10.1097/HJH.0b013e32834a4ce9
[13]   Sarveswaran, V., Kumar, S., Kumar, A., et al., 2015. A giant cystic pheochromocytoma mimicking liver abscess an unusual presentation—a case report. Clin. Case Rep., 3(1): 64-68.
doi: 10.1002/ccr3.149
[14]   Schifferdecker, B., Kodali, D., Hausner, E., et al., 2005. Adrenergic shock—an overlooked clinical entity? Cardiol. Rev., 13(2):69-72.
doi: 10.1097/01.crd.0000151679.16187.2f
[15]   List of electronic supplementary materials
[1] Po Hu, Ming-yuan Huang, Xin-yang Hu, Xiao-jie Xie, Mei-xiang Xiang, Xian-bao Liu, Jian-an Wang. Meta-analysis of C242T polymorphism in CYBA genes: risk of acute coronary syndrome is lower in Asians but not in Caucasians[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2015, 16(5): 370-379.
[2] Jian Liu, Zhao Wang, Wei-min Wang, Qi Li, Yu-liang Ma, Chuan-fen Liu, Ming-yu Lu, Hong Zhao. Feasibility of diagnosing unstable plaque in patients with acute coronary syndrome using iMap-IVUS[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2015, 16(11): 924-930.
[3] Sheng-an Su, Hong Ma, Li Shen, Mei-xiang Xiang, Jian-an Wang. Interleukin-17 and acute coronary syndrome[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2013, 14(8): 664-669.
[4] LIU Yong, DONG Sheng-guo, DONG Zhen, MAO Xin, SHI Xin-yan. Diagnosis and treatment of pheochromocytoma in urinary bladder[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2007, 8(6): 435-438.
[5] Qiao Xiao-zhi, Yang Yun-mei, Xu Zhe-rong, Yang Li-ai. Relationship between resistin level in serum and acute coronary syndrome or stable angina pectoris[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2007, 8(12): 875-880.
[6] SONG Ying, LI Meng, LI Ji-cheng, WEI Er-qing. Edaravone protects PC12 cells from ischemic-like injury via attenuating the damage to mitochondria[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2006, 7(9): 749-756.