To go international is now one of China's national guiding strategies for her academic publishing yet a hard nut to crack. Although the number of SCI cited articles written by Chinese writers has currently ranked second in the world since 2009, China's home-made journals are still scarcely enlisted among those with high impact factors and have played a literally negligible role in the world academia, for which China's academic publishers as well as related government officials have much been tormented. How to solve the problem is now a hot topic and attracts nation-wide attention. China's academic publishing has been developing for over 3 000 years, however, her internationalization process didn't virtually start until late Qing Dynasty and early Republic of China when the western missionaries established journals and set up publishing houses inside China. After her first homemade academic journal National Medical Journal of China was founded in 1915, China began her endeavor to seek opportunity to speak out in the international arena of academic publishing and has experienced lots of ups and downs. The vicissitudes that China's academic publishing has come through are worth a systematic retrospect and a research in a deep-going way. This article, one of the research achievements of The National Funding Project 13BXW016, records the efforts that the publishers have made in presenting China's academic achievements to the world, and sums up what China's academic publishing has accomplished in gaining international recognition since late Qing Dynasty, by dividing the course into 5 periods and arranges them in a chronological order: (1) period of founding (1887-1949) when both the western missionaries and pioneer Chinese publishers created journals and established publishing houses; (2) period of alternation (1949-1965) from the day when People's Republic of China was founded until the eve of so called″the Great Proletarian Cultural Revolution″. In this period newly established Chinese home-made academic journals were growing together with those left over from before 1949; (3) period of perseverance (1966-1976) when editors and publishers under-went harm and destruction but still stood fast in the havoc of the Cultural Revolution; (4) period of restoration (1978-2008) when China initiated the reform and opening-up policy and renewed her home-made academic publishing; (5) period of sustainable development (2009-) when most China's publishing houses have undertaken transformation and their publishing has generally been upgraded in technology and scale. Focusing on the right of speech, the article ends up with an emphasis on the voice of China's home-made academic publishing in the international academia by putting forward a proposal that measures should be taken to innovate the current evaluation system and to perfect the eco-environment of China's academic publishing in the internet era when China is developing along with the world at the same speed. To promote her level of internationalization, China's academic publishing should consciously abide by the internationally recognized practices and standards and be more confident in building up prestige in the World.