Please wait a minute...
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2006, Vol. 7 Issue (12): 5-    DOI: 10.1631/jzus.2006.B0969
    
Regularities in the E. coli promoters composition in connection with the DNA strands interaction and promoter activity
BEREZHNOY Andrey Yu, SHCKORBATOV Yuriy G., HISANORI Kiryu
National Scientific Center, Kharkov Physical-Technical Institute, Kharkov 61108, Ukraine; Institute of Biology, Kharkov National University, Maidan Svobody 4, Kharkov 61077, Ukraine; Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology, Koto-ku Tokyo 135-0064, Japan
Download:     PDF (0 KB)     
Export: BibTeX | EndNote (RIS)      

Abstract  The energy of interaction between DNA strands in promoters is of great functional importance. Visualization of the energy of DNA strands distribution in promoter sequences was achieved. The separation of promoters in groups by their energetic properties enables evaluation of the dependence of promoter strength on the energetic properties. The analysis of groups (clusters) of promoters distributed by the energy of DNA strands interaction in −55, −35, −10 and +6 sequences indicates their connection with the transcriptional activity.

Key wordsDNA sequence      Promoter strength      DNA chains interaction energy      DNA sequences classification     
Received: 11 May 2006     
CLC:  Q75  
Cite this article:

BEREZHNOY Andrey Yu, SHCKORBATOV Yuriy G., HISANORI Kiryu. Regularities in the E. coli promoters composition in connection with the DNA strands interaction and promoter activity. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2006, 7(12): 5-.

URL:

http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.2006.B0969     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2006/V7/I12/5

[1] CHENG Jun, TONG Zi-shuang, ZHANG Lin-xi. Scaling behavior of nucleotide cluster in DNA sequences[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2007, 8(5): 359-364.
[2] XIN Ming-xiu, ZHOU Pei-jin. Mrakia psychrophila sp. nov., a new species isolated from Antarctic soil[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2007, 8(4): 260-265.
[3] BEREZHNOY Andrey Y., SHCKORBATOV Yuriy G.. Dependence of the E. coli promoter strength and physical parameters upon the nucleotide sequence[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2005, 6(11): 3-.
[4] DUPLIJ Diana, DUPLIJ Steven. DNA sequence representation by trianders and determinative degree of nucleotides[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2005, 6( 8): 8-.
[5] CHENG Jun, ZHANG Lin-xi. Statistical properties of nucleotide clusters in DNA sequences*[J]. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2005, 6( 5): 18-.