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ZJUS-B
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2007, Vol. 8 Issue (11): 815-821    DOI: 10.1631/jzus.2007.B0815
Quantitative Genetics 鈥?Selected Papers of the 3rd International Conference on Quantitative Genetics (ICQG), 2007 Aug., Hangzhou, China     
WOMBAT—A tool for mixed model analyses in quantitative genetics by restricted maximum likelihood (REML)
MEYER Karin
Animal Genetics and Breeding Unit, University of New England, Armidale, New South Wales 2351, Australia
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Abstract  WOMBAT is a software package for quantitative genetic analyses of continuous traits, fitting a linear, mixed model; estimates of covariance components and the resulting genetic parameters are obtained by restricted maximum likelihood. A wide range of models, comprising numerous traits, multiple fixed and random effects, selected genetic covariance structures, random regression models and reduced rank estimation are accommodated. WOMBAT employs up-to-date numerical and computational methods. Together with the use of efficient compilers, this generates fast executable programs, suitable for large scale analyses. Use of WOMBAT is illustrated for a bivariate analysis. The package consists of the executable program, available for LINUX and WINDOWS environments, manual and a set of worked example, and can be downloaded free of charge from http://agbu.une.edu.au/~kmeyer/wombat.html

Key words： Software      Variance components      Genetic parameters      Mixed model      Restricted maximum likelihood     
Received: 12 September 2007     
CLC:  Q78  
  TP31  
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MEYER Karin
Cite this article:

MEYER Karin. WOMBAT—A tool for mixed model analyses in quantitative genetics by restricted maximum likelihood (REML). Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2007, 8(11): 815-821.

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http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.2007.B0815     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2007/V8/I11/815

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