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ZJUS-B
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2008, Vol. 9 Issue (6): 496-499    DOI: 10.1631/jzus.B0720011
Biomedicine     
An insulinoma with clinical and electroencephalographic features resembling complex partial seizures
Shuang WANG, Hai-tao HU, Shu-qun WEN, Zhong-jin WANG, Bao-rong ZHANG, Mei-ping DING
Department of Neurology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
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Abstract  We described a female patient with insulinoma who experienced recurrent episodes of automatism, confusion and convulsion. Furthermore, her electroencephalography (EEG) findings resembled the pattern in complex partial seizures with secondary generalization. The interictal EEG showed spikes and sharp waves, as well as focal slowing over the left temporal lobe, and the ictal EEG revealed generalized spikes and sharp waves associated with diffused slowing. She was initially misdiagnosed as pharmacoresistant epilepsy. After the insulinoma was found and surgically removed, her EEG turned normal and she was seizure-free during the 4-year follow-up. This report highlights the need for careful reassessment of all seizures refractory to medication, even for the patients associated with epileptiform discharges on EEG.

Key words： Insulinoma      Hypoglycemia      Electroencephalography (EEG)      Seizure     
Received: 20 December 2007     
CLC:  R736.7  
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Shuang WANG
Hai-tao HU
Shu-qun WEN
Zhong-jin WANG
Bao-rong ZHANG
Mei-ping DING
Cite this article:

Shuang WANG, Hai-tao HU, Shu-qun WEN, Zhong-jin WANG, Bao-rong ZHANG, Mei-ping DING. An insulinoma with clinical and electroencephalographic features resembling complex partial seizures. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2008, 9(6): 496-499.

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http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.B0720011     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2008/V9/I6/496

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