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ZJUS-B
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2006, Vol. 7 Issue (8 ): 11-    DOI: 10.1631/jzus.2006.B0660
    
Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks
HABIB Mudasser, HUSSAIN Iftikhar, IRSHAD Hamid, YANG Zong-zhao, SHUAI Jiang-bing, CHEN Ning
Department of Veterinary Microbiology, University of Agriculture, Faisalabad 38040, Pakistan; Institute of Preventive Veterinary Medicine, School of Animal Sciences, Zhejiang University, Hangzhou 310029, China
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Abstract  Infectious bursal disease virus (IBDV) was inactivated by two different chemicals—formaldehyde and binary ethylenimine (BEI). Formaldehyde was used at 0.1% and 0.2%, while BEI was used at concentrations of 0.001 and 0.002 mol/L. These four vaccines were tested for their efficiency in generating humoral immune response in different groups of broiler chicks. Both BEI-inactivated vaccines gave relatively higher antibody titers and were almost twice as efficient as formaldehyde-inactivated ones.

Key words： Infectious bursal disease virus (IBDV)      Binary ethylenimine (BEI)      Formaldehyde      Immune response     
Received: 24 March 2006     
CLC:  S855  
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HABIB Mudasser
HUSSAIN Iftikhar
IRSHAD Hamid
YANG Zong-zhao
SHUAI Jiang-bing
CHEN Ning
Cite this article:

HABIB Mudasser, HUSSAIN Iftikhar, IRSHAD Hamid, YANG Zong-zhao, SHUAI Jiang-bing, CHEN Ning. Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2006, 7(8 ): 11-.

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http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.2006.B0660     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2006/V7/I8 /11

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