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Effects of medium composition on the production of plasmid DNA vector potentially for human gene therapy |
XU Zhi-nan, SHEN Wen-he, CHEN Hao, CEN Pei-lin |
Institute Bioengineering, School of Material Science and Chemical Engineering, Zhejiang University, Hangzhou 310027, China |
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Abstract Plasmid vector is increasingly applied to gene therapy or gene vaccine. The production of plasmid pCMV-AP3 for cancer gene therapy was conducted in a modified MBL medium using a recombinant E. coli BL21 system. The effects of different MMBL comp
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Received: 10 February 2004
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