| Life Sciences & Biotechnology |
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| Evaluation of cilazapril in vasovagal syncope treatment |
| HAN Yang, JIANG Wei-li, JIN Mei-zhen, GE Wei, CHEN Tian-zhi |
| 1st Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China |
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Abstract Objective: to evaluate cilazapril in vasovagal syncope treatment. Method: eighty-six cases of VVS patients found positive in TTT tilt were medicated with 2.5 mg cilazapril daily for three months and followed up by TTT. Results: seven cases quit due to cough or unexplained reason; 79 VVS patients had no more fainting spells; 75.95% of TTT results of patients changed to negative after 3 months therapy. The before and after cilazapril treatment average blood pressures (taken in lying position) were 121/73 mm Hg (1 mm Hg=0.133kPa) and 120/76 mm Hg respectively (P>0.05); and mean heart rates were 68.63±12.37/min and 70.13±13.15/min respectively with no significant changes (P>0.05). Conclusion: Cilazapril was effective in treatment of VVS; did not affect normal blood pressure and heart rate; was safe; and had little side effect.
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Received: 02 November 2000
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