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ZJUS-A
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering)  2002, Vol. 3 Issue (3): 374-377    DOI: 10.1631/jzus.2002.0374
Life Sciences & Biotechnology     
Ultra-Cut biopsy guided by ultrasonography for liver lesions: experience of 392 clinical cases
PAN Hong-ming, FAN xiao-ming, WANG Hai-yun, WU Jin-min
Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China
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Abstract  We conducted a retrospective study of the accuracy of liver biopsies in 392 patients with liver lesions. Postbiopsy diagnosis was 297 cases of primary liver cancers, 79 cases of secondary malignant tumors, 2 cases of non-Hodgkin\'s lymphoma, 10 cases of focal nodular hyperplasia, 2 cases of chronic inflammation, 1 tuberculosis case and 1 schistosomiasis case. Biopsy provided histological diagnosis in 100% of cases, sensibility and specificity of Ultra-Cut biopsy was 98.95% and 100% for the diagnosis of malignancy respectively; positive predictive value, 100%; negative predictive value, 71.43%; and accuracy, 98.98%. We identified no major procedure related complications despite the presence of thrombocytopenia in 37.5% of cases. Pain was the only reported adverse effect of liver biopsy (10.97%), and 11 patients required analgesics. We concluded that Ultra-Cut liver biopsy was a safe and effective technique, and was invaluable in the investigation and management of patients with liver lesions.

Key words： Liver      Neoplasms      Biopsy      Ultrasonography     
Received: 26 December 2001     
CLC:  R575  
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PAN Hong-ming
FAN xiao-ming
WANG Hai-yun
WU Jin-min
Cite this article:

PAN Hong-ming, FAN xiao-ming, WANG Hai-yun, WU Jin-min. Ultra-Cut biopsy guided by ultrasonography for liver lesions: experience of 392 clinical cases. Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2002, 3(3): 374-377.

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http://www.zjujournals.com/xueshu/zjus-a/10.1631/jzus.2002.0374     OR     http://www.zjujournals.com/xueshu/zjus-a/Y2002/V3/I3/374

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