| Biomedicine |
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| Pure word deafness associated with extrapontine myelinolysis |
| Ren-jing Zhu, Zhi-su Lv, Chun-lei Shan, Ming-wei Xu, Ben-yan Luo |
| Department of Neurology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310029, China, Department of Neurology, Zhongshan Hospital, Xiamen University, Xiamen 361004, China, Department of Ultrasonography, Children's Hospital, School of Medicine, Zhejiang University, Hangzhou 310029, China, Laboratory for Higher Brain Function, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China, Department of Rehabilitation Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China |
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Abstract Extrapontine myelinolysis and pure word deafness are very uncommon disorders. Here, we report a case of a 19-year-old woman who suffered from osmotic demyelination syndrome with coincidence of typical pure word deafness. As a consequence of rapid correction of hyponatremia, the patient demonstrated an initial onset of cortical deafness, and then progressed to generalized auditory agnosia, which eventually developed into confined verbal auditory agnosia (pure word deafness). Bilateral extrapontine myelinolysis was confirmed using brain magnetic resonance imaging. This case suggests that verbal and nonverbal stimuli may involve separate thalamocortical pathways.
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Received: 02 June 2010
Published: 04 November 2010
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