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Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2007, Vol. 8 Issue (10): 704-708    DOI: 10.1631/jzus.2007.B0704
Biomedicine     
Deep lingual arterial chemoembolization of tongue carcinoma with microcapsuled anticancer drug
HE Hong, HUANG Jian-qi, PING Fei-yun, CHEN Guan-fu, ZHANG Su-zhan
Department of Stomatology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China; Cancer Institute, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
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Abstract  Objective: Microcapsule chemoembolism is a promising treatment of tumors. We describe a deep lingual arterial embolization of tongue carcinoma with microcapsuled carboplatinum. Methods: Lingual artery cast specimens from cadavers were microscopically examined, and 78 patients with tongue cancer were recruited and treated with the deep lingual arterial embolization therapy. Results: Microcapsule embolism occurred approximately at the fifth or sixth level of the deep lingual artery branches. The five-year survival rate was 88.5% (69 out of 78), and the ten-year survival rate 52.6% (41 out of 78). Conclusion: The deep lingual arterial embolization of tongue carcinoma with microcapsuled carboplatinum is an effective therapy to treat carcinoma in mid-margin or mid-body of the tongue.

Key wordsTongue carcinoma      Artery cast      Arterial chemoembolization      Deep lingual arterial embolization      Anticancer drug      Carboplatinum     
Received: 12 June 2007     
CLC:  R739.8  
Cite this article:

HE Hong, HUANG Jian-qi, PING Fei-yun, CHEN Guan-fu, ZHANG Su-zhan. Deep lingual arterial chemoembolization of tongue carcinoma with microcapsuled anticancer drug. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2007, 8(10): 704-708.

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http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.2007.B0704     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2007/V8/I10/704

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