Organ transplantation,artificial reproduction and gene therapy are the most exciting research results in the 21th Century,which will certainly greatly benefit the human society .This article discusses some important issues from the civil law and criminal law perspectives .The author puts forward the legislation proposition based on the shortcomings of our present legislation and the reference of the legislation experiences of foreign countries,hoping to fill the research gaps in biomedical law . The first part discusses the relative issues of organ transplantation .Human organ transplantation was a major breakthrough in the field of medicine in the 20th Century .It resolved the questions which drug and other traditional methods of medical treatment cannot achieve,opened up broad prospects for the treatment of certain diseases and made the limited health resources more efficient .It is one of the highest achievements of the modern biomedical science .Coming with it are the crimes which include illegal trade in human organs,illegal removal of human organs,cross-border trade,smuggling and other acts of human organs .The article starts from the concept and judgment standard of brain death,which is the legitimacy of organ transplantation .Then the author analyzes the legal issues in different steps from the selection of donator and receptor,informed consent,the use of fetus and prisoners'body organs .At last it focuses on the different regulations for different crimes in other countries,and gives advices to the legislation in our country . The second part discusses the crimes in genetic therapy .Genetic therapy is a new medical treatment that involves many risks and remains to be improved .Keen attention therefore must be paid to moral and legal issues in biology and medicine .Criminal law,however,can be applied to some perceived culpable behaviors in practicing genetic therapy with great caution only as a last resort,lest the development of sciences should be impeded by improper interpretation of law . The last part discusses artificial reproduction .As an important method of curing infertility in modern times,artificial reproduction is an important remedy for traditional and natural reproduction . While it challenges traditional ethics,artificial reproduction also puts forward challenges to the existing legal systems .Some key points such as the legal status of zygote,children's legal issues of the artificial insemination by donor,the reproductive rights of artificial insemination by donor are analyzed emphatically in details .