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浙江大学学报（理学版）
浙江大学学报（理学版）  2015, Vol. 42 Issue (6): 739-744    DOI: 10.3785/j.issn.1008-9497.2015.06.018
环境科学     
金霉素对小麦根生长的毒性效应
The toxicity of chlortetracycline to wheat root
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摘要： 四环素类抗生素因具有抗菌和促进畜禽动物生长的功效，被广泛应用于畜禽养殖业.由于畜禽对抗生素的吸收、代谢较少，30%~90%的抗生素都以本体药物的形式随畜禽粪便排出流入环境.以四环素类抗生素——金霉素为例，研究了金霉素对小麦根生长的毒性效应，建立了不同形态金霉素对小麦根系生长的毒性效应模型：〖JP〗〖SX(〗1〖〗EC50〖SX)〗=〖SX(〗f+〖〗EC+50〖SX)〗 + 〖SX(〗f0〖〗EC050〖SX)〗 + 〖SX(〗f-〖〗EC-50〖SX)〗 + 〖SX(〗f2-〖〗EC2-50〖SX)〗，得到各形态金霉素对小麦根毒性强弱的排序：二价阴离子态>一价阴离子态>中性态>阳离子态，共存Ca2+对金霉素毒性的影响与Ca2+以及金霉素的浓度有关.
关键词： 金霉素;  小麦根;  毒性效应    
Abstract: Antibiotics are widely used in livestock and poultry industry for their growth promoting and disease preventing effects. Being poorly absorbed and metabolized by animals, about 30% to 90% of antibiotics would get into the environment as original form. In this paper, chlortetracycline (CTC), as an example for tetracycline class antibiotics, was studied for its toxicity to wheat roots. A toxicity model was built for the influence of different CTC forms on the root growth inhibition:〖SX(〗1〖〗EC50〖SX)〗=〖SX(〗f+〖〗EC+50〖SX)〗 + 〖SX(〗f0〖〗EC050 + 〖SX(〗f-〖〗EC-50〖SX)〗 + 〖SX(〗f2-〖〗EC2-50〖SX)〗. The toxicity of various forms of CTC is followed as CTC2->CTC->CTC0>CTC+. The effects of coexisted Ca2+ on the toxicity of CTC is related to the concentrations of both Ca2+ and CTC.
出版日期: 2015-07-01
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倪群丽
梁 兰
徐 鑫
林 琦

引用本文:

倪群丽， 梁 兰， 徐 鑫， 林 琦. 金霉素对小麦根生长的毒性效应[J]. 浙江大学学报（理学版）, 2015, 42(6): 739-744.

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https://www.zjujournals.com/sci/CN/Y2015/V42/I6/739

[1] 贺筱蓉;李永泉;赵小立;刘惠宾;周红军. 原生质体诱变选育去甲基金霉素高产菌[J]. 浙江大学学报（理学版）, 1997, 24(2): 170-177.