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浙江大学学报（医学版）
J Zhejiang Univ (Med Sci)  2017, Vol. 46 Issue (1): 89-91    DOI: 10.3785/j.issn.1008-9292.2017.02.13
    
Iodine 131 joint radio frequency ablation treatment for child with hyperthyroidism goiter: one case report
CHEN Yonghua1(),LIANG Li1,*(),FANG Yanlan1,WANG Chunlin1,LI Linfa2,JIANG Tian'an3
(1) Department of Pediatrics, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
(2) Department of Nuclear Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
(3) Department of Ultrasonography, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
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Abstract  

A 12-year-old girl presented with a history of cervical mass, and one week of throat discomfort and dyspnea. Five years ago, the patient was diagnosed as Hashimoto's thyroiditis and hyperthyroidism; she received antithyroid drug treatment, but the result was not satisfactory. B-ultrasonic showed that the size of thyroid gland was 8.1 cm×3.2 cm in the left and 8.2 cm×4.8 cm in the right. After iodine 131 combined with radiofrequency ablation (RFA) treatment, throat discomfort and recumbent breathing difficulties disappeared, and B-ultrasonic showed that the size of thyroid reduced to 2.3 cm×1.7 cm (left) and 2.8 cm×2.0 cm (right). No recurrence was observed during the two and a half years of follow-up.

Key words： Iodine radioisotopes/therapeutic use      Catheter ablation      Hyperthyroidism/drug therapy      Goiter/drug therapy      Goiter/complications      Critical illness      Child      Case reports     
Received: 16 October 2016      Published: 06 July 2017
CLC:  R725.8  
Corresponding Authors: LIANG Li     E-mail: 21518037@zju.edu.cn;zdliangli@163.com
About author: LIANG Li, E-mail:zdliangli@163.com
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CHEN Yonghua
LIANG Li
FANG Yanlan
WANG Chunlin
LI Linfa
JIANG Tian'an
Cite this article:

CHEN Yonghua,LIANG Li,FANG Yanlan,WANG Chunlin,LI Linfa,JIANG Tian'an. Iodine 131 joint radio frequency ablation treatment for child with hyperthyroidism goiter: one case report. J Zhejiang Univ (Med Sci), 2017, 46(1): 89-91.

URL:

http://www.zjujournals.com/med/10.3785/j.issn.1008-9292.2017.02.13     OR     http://www.zjujournals.com/med/Y2017/V46/I1/89


碘131联合射频消融治疗儿童甲状腺功能亢进症伴重度甲状腺肿一例

一例12岁8个月女童，发现颈部肿块5年余，喉部不适、呼吸困难一周入院。患儿5年前被诊断为“桥本甲状腺炎、甲状腺功能亢进症”，药物治疗后甲状腺功能仍有波动。本次入院后颈部超声检查提示左侧甲状腺大小为8.1 cm×3.2 cm，右侧为8.2 cm×4.8 cm。行碘131联合射频消融治疗后，患儿喉部不适、呼吸困难症状消失，超声检查提示左侧甲状腺缩小至2.3 cm×1.7 cm，右侧缩小至2.8 cm×2.0 cm。随访两年半，无复发。


关键词： 碘放射性同位素/治疗应用,  导管消融术,  甲状腺功能亢进症/药物疗法,  甲状腺肿/药物疗法,  甲状腺肿/并发症,  危重病,  儿童,  病例报告 
检查时间 左侧 峡部 右侧
治疗前 8.1 cm×3.2 cm，多枚低回声结节，其中一枚大小约1.8 cm×0.5 cm 1.3 cm 8.2 cm×4.8 cm，多枚低回声结节，其中一枚大小约2.2 cm×1.0 cm
碘131治疗后 3.1 cm×2.0 cm，多枚混合回声结节，较大者约1.3 cm×0.4 cm 1.5 cm 3.6 cm×3.0 cm，多枚混合回声结节，较大者约2.1 cm×1.4 cm
射频消融后 2.9 cm×2.6 cm，多枚混合回声结节，较大者约1.3 cm×1.0 cm 1.3 cm 3.5 cm×2.8 cm，多枚混合回声结节，较大者约2.0 cm×1.8 cm
射频消融后半年 2.3 cm×1.7 cm，等回声结节0.7 cm×0.6 cm 0.6 cm 2.8 cm×2.0 cm，多枚混合回声结节，较大者约1.3 cm×0.9 cm
Tab 1 B-ultrasonic showed thyroid size before and after iodine 131 joint radiofrequency ablation treatment
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