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浙江大学学报（医学版）
J Zhejiang Univ (Med Sci)  2020, Vol. 49 Issue (2): 245-248    DOI: 10.3785/j.issn.1008-9292.2020.03.12
    
Management of a colon cancer patient complicated with COVID-19
YE Ziqi(),HONG Yun,WU Xiuhua,HONG Dongsheng,ZHANG Yanfang,DONG Xihao,RAO Yuefeng*(),LU Xiaoyang*()
Department of Pharmacy, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
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Abstract  

Objective: To explore the feasibility of radical resection for cancer patients complicated with coronavirus disease 2019 (COVID-19). Methods: The management and clinical outcome of a sigmoid cancer patient with COVID-19 were analyzed. Results: The inflammation indicators and fever of this patient were effectively controlled and the lung lesions remained stable after active anti-viral treatment, then the radical colorectomy was performed after the viral negative conversion for twice. Conclusion: The case indicates that radical resection can be performed in SARS-CoV-2 patients with twice-negative SARS-CoV-2 nucleic acid testing results.

Key words： Coronavirus disease 2019      Severe acute respiratory syndrome coronavirus 2      Novel coronavirus pneumonia      Colon cancer      Radical resection      Timing of treatment     
Received: 04 March 2020      Published: 27 March 2020
CLC:  R730.5  
Corresponding Authors: RAO Yuefeng,LU Xiaoyang     E-mail: ziqiye@zju.edu.cn;raoyf@zju.edu.cn;luxiaoyang@zju.edu.cn
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YE Ziqi
HONG Yun
WU Xiuhua
HONG Dongsheng
ZHANG Yanfang
DONG Xihao
RAO Yuefeng
LU Xiaoyang
Cite this article:

YE Ziqi,HONG Yun,WU Xiuhua,HONG Dongsheng,ZHANG Yanfang,DONG Xihao,RAO Yuefeng,LU Xiaoyang. Management of a colon cancer patient complicated with COVID-19. J Zhejiang Univ (Med Sci), 2020, 49(2): 245-248.

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http://www.zjujournals.com/med/10.3785/j.issn.1008-9292.2020.03.12     OR     http://www.zjujournals.com/med/Y2020/V49/I2/245


一例肿瘤合并2019冠状病毒病(COVID-19)患者的治疗决策分析

目的: 探讨亟待进行肿瘤根治术的患者合并2019冠状病毒病（COVID-19）后如何选择手术治疗时机。方法: 详细分析1例乙状结肠癌合并COVID-19患者的治疗过程，以及该患者在病毒两次转阴后进行根治性手术后的恢复情况。结果: 患者术后恢复良好，炎症指标、发热等临床表现改善，肺部病灶也维持稳定。结论: 对于亟待进行肿瘤根治术且合并COVID-19的患者，在符合病毒核酸检测两次阴性之后进行肿瘤根治术是可行的。


关键词： 2019冠状病毒病,  严重急性呼吸综合征冠状病毒2,  新型冠状病毒肺炎,  结肠癌,  根治性手术,  治疗时机 
检测时间 白细胞计数
(×109/L)		 中性粒细胞计数
(×109/L)		 血红蛋白
(g/L)		 淋巴细胞计数
(×109/L)		 血小板计数
(×109/L)		 C反应蛋白
(mg/L)		 降钙素原
(ng/mL)		 丙氨酸转氨酶
(U/L)		 天冬氨酸转氨酶
(U/L)		 碱性磷酸酶
(U/L)		 总胆红素
(μmol/L)		 白蛋白
(g/L)		 肌酐
(μmol/L)
术前 3.6 2.9 84 0.4 66 70 0.18 33 22 66 43.8 34.7 43
术后1 d 4.2 3.4 108 0.9 49 107 0.37 21 17 61 30.0 31.6 48
术后3 d 11.8 10.1 99 2.1 75 95 0.23 31 35 88 23.7 31.7 43
术后6 d 6.6 5.0 117 1.6 67 86 0.19 17 18 96 27.7 30.3 45
Tab 1 Laboratory examination of a COVID-19 patient before and after sigmoid colon cancer radical resection
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