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浙江大学学报（医学版）
J Zhejiang Univ (Med Sci)  2020, Vol. 49 Issue (1): 118-123    DOI: 10.3785/j.issn.1008-9292.2020.02.13
    
Research progress on electroencephalogram characteristics of anti-N-methyl-D-aspartate receptor encephalitis
LIU Xiaoxiao(),GUO Liqiong,LIANG Cheng*()
The Second Clinical Medical College, Lanzhou University, Lanzhou 730030, China
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Abstract  

Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a kind of autoimmune disease aiming at NR1 subunit of NMDA receptor. In the early stage, functional damage is the main cause. Electroencephalogram (EEG) can reflect the abnormal brain function by recording the changes of EEG signals. The common EEG patterns of anti NMDA receptor encephalitis are slow wave abnormality, epileptic discharge, a large number of β activity, extreme delta brush, etc. Here we review the waveform characteristics, origin, pathogenesis and clinical value of EEG in patients with NMDA receptor encephalitis.

Key words： Receptors, N-methyl-D-aspartate/encephalitis      Autoimmunity/disease      Electroencephalography      Brain waves/abnormal      Review     
Received: 30 September 2019      Published: 08 June 2020
CLC:  R742  
  R741.044  
Corresponding Authors: LIANG Cheng     E-mail: 287985748@qq.com;hongyan200107@126.com
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LIU Xiaoxiao
GUO Liqiong
LIANG Cheng
Cite this article:

LIU Xiaoxiao,GUO Liqiong,LIANG Cheng. Research progress on electroencephalogram characteristics of anti-N-methyl-D-aspartate receptor encephalitis. J Zhejiang Univ (Med Sci), 2020, 49(1): 118-123.

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http://www.zjujournals.com/med/10.3785/j.issn.1008-9292.2020.02.13     OR     http://www.zjujournals.com/med/Y2020/V49/I1/118


抗N-甲基-D-天冬氨酸受体脑炎患者脑电图特点的研究进展

抗N-甲基-D-天冬氨酸（NMDA）受体脑炎是一种针对NMDA受体NR1亚基的自身免疫性疾病，早期以功能性损伤为主，脑电图检查通过记录脑电信号的变化，可以敏感地反映脑功能异常。抗NMDA受体脑炎较为常见的脑电图特点为慢波性异常、癫痫样放电、大量β活动、极度δ刷状波等。本文从上述脑电图模式的波形特点、起源部位、发生机制、临床价值等方面，综述抗NMDA受体脑炎患者的脑电图特点研究概貌。


关键词： 受体, N-甲基-D-天冬氨酸/脑炎,  自身免疫性/疾病,  脑电描记术,  脑电波/异常,  综述 
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