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Journal of ZheJiang University(Medical Science)  2014, Vol. 43 Issue (4): 501-503    DOI: 10.3785/j.issn.1008-9292.2014.04.007
    
Surgical treatment combined with oral administration of indomethacin for eosinophilic granuloma of the skull: report of a pediatric case
LI Jiang, CHEN Fu-ting, XU Jiang-rong
Department of Neurosurgery, Affiliated Hospital , College of Medicine, Ningbo University, Ningbo 315020, China
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Abstract  A 13-year-old girl presented headache for 5 d upon admission to hospital. An initial CT revealed 3 lesions located in her skull, the sizes of which were 2.5 cm×3.2 cm,1.2 cm×1.0 cm,0.3 cm×0.3 cm, respectively. The largest lesion was resected by surgery and confirmed as eosinophilic granuloma by pathology. After surgery, she took oral indomethacin 25 mg b.i.d for 3 months and tolerated it well. CT scan was performed 3 months and 1 year later, and the results showed that the unresected lesions shrank progressively and the defected bones were regenerated and healed one year later after operation.

Received: 08 November 2013     
Cite this article:

LI Jiang,et al. Surgical treatment combined with oral administration of indomethacin for eosinophilic granuloma of the skull: report of a pediatric case. Journal of ZheJiang University(Medical Science), 2014, 43(4): 501-503.

URL:

http://www.zjujournals.com/xueshu/med/10.3785/j.issn.1008-9292.2014.04.007     OR     http://www.zjujournals.com/xueshu/med/Y2014/V43/I4/501


手术联合吲哚美辛口服治疗颅骨多发嗜酸细胞肉芽肿患儿一例

一例13岁女孩因为头痛5 d入院,CT检查提示其颅骨三处病变分别为大小约2.5 cm×3.2 cm,1.2 cm×1.0 cm,0.3 cm×0.3 cm。患者最大一处病变接受手术切除,术后病理证实为嗜酸细胞肉芽肿。而后给予其吲哚美辛片25 mg每天两次口服,应用3个月,患者耐受良好。术后3个月及1年CT复查提示未手术处病变进行性缩小,术后1年时新生骨组织基本替代原病变缺损。
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