Research advance on bacteriophage therapy in bacterial infection
PEI Jingliang1，FU Yurong2
1.Affiliated Hospital of Weifang Medical University，Key Laboratory of Clinical Diagnosis in Universities of Shandong，Weifang 261031; 2.Department of Microbiology，Weifang Medical University，Weifang 261053;
Bacteriophage is a bacterium dependent virus.It has unique advantages in the treatment of bacterial infection，especially infection caused by drug-resistant bacteria.Its metabolic kinetics and route of administration are the current research focus.Bacteriophage lytic enzyme，as a new therapeutic method，has more advantages than active bacteriophage.This review is focused on the recent progress in bacteriophage research，including the mechanism of bacteria lysis，the route of administration，the application of genetic engineering，etc.
Received: 03 September 2012
Published: 25 November 2013