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Journal of ZheJiang University(Medical Science)  2013, Vol. 42 Issue (6): 700-704    DOI: 10.3785/j.issn.1008-9292.2013.06.019
Research advance on bacteriophage therapy in bacterial infection
PEI Jingliang1,FU Yurong2
1.Affiliated Hospital of Weifang Medical University,Key Laboratory of Clinical Diagnosis in Universities of Shandong,Weifang 261031; 2.Department of Microbiology,Weifang Medical University,Weifang 261053;
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Bacteriophage is a bacterium dependent virus.It has unique advantages in the treatment of bacterial infection,especially infection caused by drug-resistant bacteria.Its metabolic kinetics and route of administration are the current research focus.Bacteriophage lytic enzyme,as a new therapeutic method,has more advantages than active bacteriophage.This review is focused on the recent progress in bacteriophage research,including the mechanism of bacteria lysis,the route of administration,the application of genetic engineering,etc.

Key wordsBacteriophages      Lytic enzymes      Route of administration      Bacterial infection/therapy     
Received: 03 September 2012      Published: 25 November 2013
Cite this article:

PEI Jingliang,FU Yurong. Research advance on bacteriophage therapy in bacterial infection. Journal of ZheJiang University(Medical Science), 2013, 42(6): 700-704.

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关键词: 细菌噬菌体,  裂解酶,  给药途径,  细菌感染/治疗 
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