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Journal of ZheJiang University(Medical Science)  2011, Vol. 40 Issue (5): 550-554    DOI: 10.3785/j.issn.1008-9292.2011.05.015
    
Aortic elastic properties and its clinical significance in intracranial aneurysms
PU Zhao-xia,YOU Xiang-dong,WENG Wen-chao,WANG Jian-an,SHI Jian
The Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China
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Abstract  Objective: To investigate the aortic elastic properties and its clinical significance in intracranial aneurysms (IAs).
Methods: One hundred and seven IAs patients (57 with hypertension) and 108 healthy subjects were recruited.The internal aortic diameters in systole and diastole were measured by the M-mode echocardiography,the aortic elasticity indexes were calculated and compared.
Results: The aortic distensibility (DIS) was lower and the aortic stiffness index (SI) was higher in IAs patients than those in controls (both P<0.001).DIS was lower and SI was higher in IAs patients with hypertension (IAs-HP) than those in IAs with no hypertension (P<0.001).Similar results were obtained when the aortic elasticity index were adjusted for body surface area and body mass index.
Conclusion: Abnormal aortic elasticity is a common finding in IAs patients and hypertension is closely related to the severity of aortic elasticity.


Key wordsIntracranial aneurysm/ultrasonogr      Echocardiography      Elasticity      Aorta      Hypertension     
Published: 25 September 2011
Cite this article:

. Aortic elastic properties and its clinical significance in intracranial aneurysms. Journal of ZheJiang University(Medical Science), 2011, 40(5): 550-554.

URL:

https://www.zjujournals.com/med/10.3785/j.issn.1008-9292.2011.05.015     OR     https://www.zjujournals.com/med/Y2011/V40/I5/550


颅内动脉瘤患者主动脉弹性功能变化及临床意义

目的:观测颅内动脉瘤患者的主动脉弹性功能,探讨其功能变化的临床意义。
方法:选择107例颅内动脉瘤患者(其中伴发高血压者57例)和108例正常对照者,M型超声心动图测量升主动脉收缩期(AoS)及舒张期(AoD)内径,计算并比较各组主动脉弹性功能指标。
结果:①与正常对照组比较:颅内动脉瘤高血压组、非高血压组患者的主动脉膨胀性(aortic distensibility,DIS)均明显降低(P<0.001),而僵硬度(aortic stiffness index,SI)明显增加(P<0.001)。②与颅内动脉瘤非高血压组比较,伴有高血压的颅内动脉瘤患者DIS明显降低(P<0.001),而SI有所升高(P<0.05)。三组间经体表面积、体重指数校正后的校正值亦存在同样规律。
结论:颅内动脉瘤患者均存在主动脉弹性功能的减退,且高血压是引起该疾患主动脉弹性功能进一步减退的原因之一。

关键词: 颅内动脉瘤/超声检查,  超声心动描记术,  弹性,  主动脉,  高血压 
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