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Journal of ZheJiang University(Medical Science)  1996, Vol. 25 Issue (6): 263-266    DOI: 10.3785/j.issn.1008-9292.1996.06.008
    
THE OPTIMAL AGE FOR SURGICAL TREATMENT OF CRANIOFACIAL DYSOSTOSIS
Ren Zaigao1, Li Runchun2, Liu Zudong3, et al
Second Affiliated Hospital, Zhejiang Medical University
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Abstract  

In the treatment of craniofacial dysostosis with monobloc frontofacial advancement, the curative effect and surgically caused life-threatening complications are known to be related to the age of patients. However, the optimal age for operation needs further exploration. A follow-up study carried out in 33 patients with a large pedigree of craniofacial dysostosis has demonstrated the markedly characteristic changes in displasia course of clildren patients to be the widening of the extraorbital intermargin distance and inner intercanthi distance. Such distances widened with age from childhood to adult in a self-control manner. The relative ratio of the increments was regarded as the increase rate of deformity. And the rate below 5%was taken as an indication that fell into a fundamentally definite pattern of displasia, which stopped its development at the age of eight to ten. These observations suggest that the suitable age for operation be eight to ten years old.



Key wordsofacial dysostosis/genetics      Craniofacial dysostosis/surg      Follow-up studies      Age-Factors     
Received: 26 January 1996      Published: 25 November 1996
Cite this article:

Ren Zaigao, Li Runchun, Liu Zudong, et al. THE OPTIMAL AGE FOR SURGICAL TREATMENT OF CRANIOFACIAL DYSOSTOSIS. Journal of ZheJiang University(Medical Science), 1996, 25(6): 263-266.

URL:

https://www.zjujournals.com/med/10.3785/j.issn.1008-9292.1996.06.008     OR     https://www.zjujournals.com/med/Y1996/V25/I6/263


从颅面骨发育过程探讨颅面骨发育不全症手术矫治合适年龄

以整块额面骨徒前术矫治颅面骨发育不全症的疗效及致死性并发症,已知与手术年龄有关,但最适年龄尚未明确。本文研究有33例颅面骨发育不全症的大家系,发现患儿发育过程中变化最显着的特征是两眼眶外缘距离和两眼内眦距离增宽。我们将这两项成年前后自身对照增长的相对值,称为畸值增长率,以<5%作为发育基本定型的标志。发现基本定型的年龄是8~10岁,故手术以8~10岁为宜。


关键词: 颅面骨发育不全/遗传学,  颅面骨发育不全/外科手术,  随访研究,  年龄因素 
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