Please wait a minute...
浙江大学学报（医学版）
Journal of ZheJiang University(Medical Science)  1990, Vol. 19 Issue (2): 56-58    DOI: 10.3785/j.issn.1008-9292.1990.02.003
    
PLATELET AGGREGATION AND THE LEVEL OF PLASMA THROMBOXANE B2 IN PATIENTS WITH OLD MYOCARDIAL INFARCTION
Zhang Xiaogang, Lou Fuqing, Lu Junsheng, et al
Department of internal medicine of the second affiliated hospital
Download: HTML ( )    PDF(263KB)
Export: BibTeX | EndNote (RIS)      

Abstract  

This paper reports the platelet aggregation and the level of plasma throm-boxane B2(TXB2) in patients with old myocardial infarction(OMI). The platelet aggregation was induced by adenosine diphosphate(1.25 μmol,2.5μmol) and adrenaline(1 μmol,2 μmol)and the platelet aggregation ratio in the first minute and the maximal platelet aggregation ratio were studied.The results showed that the platelet aggregation described above and the level of plasma TXB_2 in the 25 patients with OMI we treated were significantly higher than those in the control group(P<0.01),revealing a hypercoagulation state in patients with OMI.The technical factors which would affect the platelet aggregation were discussed as well.

Key words： Myocardial infarction/pathophysiol      Platelet aggregation      Thromboxane B2/blood     
Received: 16 December 1988      Published: 25 March 1990
Service
E-mail this article
Add to my bookshelf
Add to citation manager
E-mail Alert
RSS
Articles by authors
Cite this article:

Zhang Xiaogang, Lou Fuqing, Lu Junsheng, et al. PLATELET AGGREGATION AND THE LEVEL OF PLASMA THROMBOXANE B2 IN PATIENTS WITH OLD MYOCARDIAL INFARCTION. Journal of ZheJiang University(Medical Science), 1990, 19(2): 56-58.

URL:

https://www.zjujournals.com/med/10.3785/j.issn.1008-9292.1990.02.003     OR     https://www.zjujournals.com/med/Y1990/V19/I2/56


陈旧性心肌梗塞病人的血小板聚集性和血栓素B2水平

本文观察了25名陈旧性心肌梗塞病人的血小扳聚集性和血浆血栓素B2水平。血小板聚集性以1.25μmol、2.5μmol ADP和1μmol、2μmol肾上腺素为诱导剂,以1min聚集率、最大聚集率和自发聚集率为指标。结果表明:陈旧性心肌梗塞病人的上述各项指标均高于正常对照组(P<0.01);放射免疫法测定血栓素B2示:陈旧性心肌梗塞病人的血浆血栓素B2水平明显高于正常对照组(P


关键词： 心肌梗塞/病理生理学,  血小板凝集,  血栓素B2/血液 
[1] YAN Shen-qiang, MAO Ying-ying, ZHONG Gen-long, ZHANG Sheng, LOU Min. Safety of intravenous thrombolysis in cerebral microbleeds patients with prior antiplatelet therapy[J]. Journal of ZheJiang University(Medical Science), 2015, 44(6): 618-624.
[2] LI Xiao-jing，CHEN Xiao-min. Association between clopidogrel resistance and polymorphism of platelet adenosine diphosphate receptor in patients with coronary atherosclerotic disease[J]. Journal of ZheJiang University(Medical Science), 2014, 43(3): 333-338.
[3] . Effect of benzo(a)pyrene on platelet aggregation and expression of P-selectin[J]. Journal of ZheJiang University(Medical Science), 2011, 40(1): 51-56.
[4] Lin Youmin, Kang Manli. Relationship between Plasma Levels of TXA2、PGI2 and Pulmonary Artery Hypertension in Congenital Ventricular Septal Defect[J]. Journal of ZheJiang University(Medical Science), 1999, 28(2): 62-64.
[5] Yu Yuxing, Xie Tao, Pan Yizheng. STUDY ON CONTENTS OF PLASMA 6-KETO-PGF1α ANDTXB2 IN PATIENTS WITH MIGRAINE DURING HEADACHE-FREE PERIOD[J]. Journal of ZheJiang University(Medical Science), 1995, 24(1): 21-23.
[6] Zhang Xiaogang, Lou Fuqing, Lu Junsheng. FURTHER STUDIES OF THE EFFECTS OF TEA FLAVANOLS ON PLATELET FUNC TIONS[J]. Journal of ZheJiang University(Medical Science), 1989, 18(6): 244-247.
[7] Xie Qiangmin, Zheng Qingjun, Bian Rulian. INHIBITION OF PLATELET AGGREGATION BY TETRANDRINE[J]. Journal of ZheJiang University(Medical Science), 1989, 18(1): 7-10.
[8] Wang Zhensheng, et al . THE ANTICOAGULANT, FIBRINOLYSIS PROMOTING AND PLATELET AGGREGATION INHIBITING ACTION OF TEA FLAVANOLS IN VITRO[J]. Journal of ZheJiang University(Medical Science), 1988, 17(4): 149-152.