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浙江大学学报（医学版）
浙江大学学报（医学版）  2017, Vol. 46 Issue (6): 662-665    DOI: 10.3785/j.issn.1008-9292.2017.12.14
病例报告     
胰岛素瘤合并继发性肾上腺皮质功能不全一例
李瑶(),陈慧*()
兰州大学第二医院内分泌代谢科, 甘肃 兰州 730030
A case of insulinoma complicated with secondary adrenal insufficiency
LI Yao(),CHEN Hui*()
Department of Endocrinology, the Second Hospital of Lanzhou University, Lanzhou 730030, China
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摘要：

一例中年男性反复发生低血糖的患者，经过各项相关检查诊断为胰岛素瘤。患者促肾上腺皮质激素和皮质醇水平低，推测存在继发性肾上腺皮质功能不全，补充糖皮质激素后行胰岛素瘤切除术。术后停激素替代疗法，患者促肾上腺皮质激素和皮质醇水平正常，生理节律恢复。
关键词： 胰岛素瘤/外科学;  低血糖症;  肾上腺功能减退/并发症;  病例报告    
Abstract:

A middle-aged male patient with recurrent hypoglycemia was diagnosed as insulinoma according to the symptoms and the laboratory tests. Laboratory tests also showed low cortisol and adrenocortico-tropic hormone (ACTH) levels, therefore adrenal insufficiency was diagnosed and hydrocortisone was given. The hormone replacement therapy was terminated after surgery, and ACTH and cortisol levels returned to normal.
Key words: Insulinoma/surgery    Hypoglycemia    Adrenal insufficiency/complications    Case reports
收稿日期: 2017-06-22 出版日期: 2017-12-25
CLC:  R58  
通讯作者: 陈慧     E-mail: liyao1192@163.com;chenhui@lzu.edu.cn
作者简介: 李瑶(1992-), 女, 硕士研究生, 主要从事肾上腺皮质功能减退及自身免疫性甲状腺疾病的研究; E-mail:liyao1192@163.com; https://orcid.org/0000-0001-5110-0106
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引用本文:

李瑶,陈慧. 胰岛素瘤合并继发性肾上腺皮质功能不全一例[J]. 浙江大学学报（医学版）, 2017, 46(6): 662-665.

LI Yao,CHEN Hui. A case of insulinoma complicated with secondary adrenal insufficiency. J Zhejiang Univ (Med Sci), 2017, 46(6): 662-665.

链接本文:

http://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.2017.12.14    或    http://www.zjujournals.com/med/CN/Y2017/V46/I6/662

图 1  患者术前腹部增强CT图像
图 2  患者胰腺组织病理组织学检查所见(HE染色)
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