Objective:To study the dynamic changes of serum CK,CK-MB,LDH,α-HBDH,AST and cTnT levels in patients with myocardial ischaemic cell damage.Methods:Serum levels of AST,LDH,α-HBDH,CK,CK-MB and cTnT of 32 patients who underwent cardiac operations (cardiac operation group),80 healthy people (control group I) and 30 patients with skeletal muscle damage(control group Ⅱ) were determined by dynamics and ELISA methods.Results:The serum levels of CK,CK-MB,LDH,α-HBDH and AST of control group Ⅱ were higher than those of control group I with statistical significance (P<0.05). All these biochemical markers increased after cardiac operations.The mean peak value of cardiac cTnT was 28 times higher than the reference value.The mean peak value of CK-MB was 16 times higher than the reference value.Serum cTnT increased most rapidly and serum concentrations reached a peak in about 6 hours after operations,and persisted for one to three days.Serum CK-MB concentrations reached a peak in about 12 hours after operations.Other biochemical markers reached their peak values more slowly and persisted for a longer time Conclusion:Serum cTnT is a more useful indicator for ischemic myocardial cell damage than other biochemical markers studied.