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浙江大学学报（医学版）
浙江大学学报（医学版）  2015, Vol. 44 Issue (1): 74-78,84    DOI: 10.3785/j.issn.1008-9292.2015.01.012
原著     
生物补片应用于腹腔镜抗反流手术治疗胃食管反流病疗效观察
吕杰敏, 黄迪宇, 林辉, 王先法
浙江大学医学院附属邵逸夫医院普外科, 浙江 杭州 310016
Laparoscopic anti-reflux surgery with biological mesh in treatment of gastroesophageal reflux disease
LV Jie-min, Huang Di-yu, Lin Hui, Wang Xian-fa
Department of General Surgery, Sir Run Run Shaw Hosptial, Zhejiang University School of Medicine, Hangzhou 310016, China
 全文: PDF(2386 KB)  
摘要：

目的:评价生物补片应用于腹腔镜抗反流手术治疗胃食管反流病的效果.方法:回顾2012年12月至2014年4月在浙江大学医学院附属邵逸夫医院普外科收治的20例有典型临床症状的胃食管反流病患者,接受腹腔镜食管裂孔修补加360°胃底折叠术,使用4层猪小肠黏膜下层基质补片进行食管裂孔加强修补.结果:20例患者的腹腔镜手术均成功,未发生术中并发症.术后症状均消失,随访3～18个月未复发,有6例患者出现吞咽困难,其中5例经保守治疗好转,1例接受食管下端扩张术.结论:腹腔镜抗反流手术治疗胃食管反流病时,使用4层猪小肠黏膜下层基质补片进行食管裂孔加强修补的效果令人满意.
关键词： 胃食管反流/外科学;  食管裂孔疝/外科学;  生物相容性材料;  修复外科手术;  腹腔镜检查;  治疗结果;  回顾性研究;  随访研究    
Abstract:

Objective: To evaluate the application of biological mesh in laparoscopic anti-reflux procedure for gastroesophageal reflux disease (GERD). Methods: The clinical data of 20 consecutive GERD patients underwent anti-reflux surgery in Sir Run Run Shaw Hospital from December 2012 to April 2014 were retrospectively analyzed. The laparoscopic hiatal repair with 360 fundoplicaiton was performed and the biological mesh (BiodesignTM, Surgsis®) was implanted for reinforcement of hiatal repair. Results: All laparoscopic procedures were successful, no conversion and no intra-operative complications occurred. The pre-operative complains were relieved in all patients, and no recurrence was observed during 3-18 month of follow-up. Six patients got dysphagia after operation; 5 of them were controlled through medication and psychological induction; 1 received esophageal dilatation by bougie. Conclusion: The application of biological mesh in laparoscopic anti-reflux procedure for gastroesophageal reflux disease is satisfactory.
Key words: Gastroesophageal reflux/surgery    Hernia, hiatal/surgery    Biocompatible materials    Reconstructive surgical procedures    Laparoscopy    Treatment outcome    Retrospective studies    Follow-up studies
收稿日期: 2014-07-21
CLC:  R656  
基金资助:

浙江省重点科技创新团队计划(2009R50040).
通讯作者: 王先法(1965-),男,硕士,主任医师,硕士生导师,从事普通外科学、微创外科学研究;E-mail: wangxf@srrh.com     E-mail: wangxf@srrh.com
作者简介: 吕杰敏(1987-),男,硕士,住院医师,从事普通外科学、微创外科学研究;E-mail: zhedastudent@163.com
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引用本文:

吕杰敏, 黄迪宇, 林辉, 王先法. 生物补片应用于腹腔镜抗反流手术治疗胃食管反流病疗效观察[J]. 浙江大学学报（医学版）, 2015, 44(1): 74-78,84.

LV Jie-min, Huang Di-yu, Lin Hui, Wang Xian-fa. Laparoscopic anti-reflux surgery with biological mesh in treatment of gastroesophageal reflux disease. Journal of ZheJiang University(Medical Science), 2015, 44(1): 74-78,84.

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http://www.zjujournals.com/xueshu/med/CN/10.3785/j.issn.1008-9292.2015.01.012    或    http://www.zjujournals.com/xueshu/med/CN/Y2015/V44/I1/74

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