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浙江大学学报（医学版）
浙江大学学报（医学版）  1998, Vol. 27 Issue (4): 157-159    DOI: 10.3785/j.issn.1008-9292.1998.04.005
论著     
小剂量氟哌啶预防腹腔镜胆囊摘除术后恶心呕吐的研究
周大春, 陈洁, 伍伟明
浙江医科大学附属邵逸夫医院麻醉科
Low-Dose Droperidol Prevents Postoperative Nausea and Vomiting after Laparoscopic Cholecystectomy
Zhou Dachun, Chen Jie, Wu Weiming
Department of Anesthesiology, Sir Run Run Shaw Hospital, Zhejiang Medical University
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摘要： 目的:研究麻醉时用小剂量(1.0mg)氟哌啶对腹腔镜胆囊摘除术(LC)术后恶心呕吐的预防效果及其不良反应。方法:观察78例LC病人,用药组38例,对照组40例,对比术中平均动脉压(MAP)、HR、麻醉恢复室(PACU)评分、术后恶心呕吐发生率等。结果:用药组恶心呕吐发生率(13.2%)明显低于对照组(32.5%)(P<0.05),MAP、HR、PACU评分在组间无显著差异。结论:小剂量氟哌啶能有效预防LC术后恶心呕吐,对麻醉无明显影响。
关键词： 腹腔镜胆囊切除术/副作用;  恶心/预防和控制;  呕吐/预防和控制;  氟哌利多/投药和剂量    
Abstract: Objective: To evaluate the efficacy and adverse effects of low-dose droperidol(1.0 mg) in preventing postoperative nausea and vomiting (PONV) of laparoscopic cholecystectomy (LC). Methods: Seventy-eight LC patients under standardized anesthesia were randomly divided into a prophylactic group (n=38) and a control group (n=40). Parameters studied included MAP,HR changes in surgery, post-anesthesia care unit (PACU),score and PONV episodes after surgery recorded by "blinded" nurses. Results: The incidence of PONV in the prophylactic group (13.5%) was significantly lower than that of the control group (32.5%), (P<0.05). MAP,HR in surgery, PACU score and PACU observation time showed no significant difference between the two groups (P>0.05). Conclusion: Low-dose droperidol (1.0 mg) administered in anesthesia reduces the incidence of PONV of LC with neither circulation interference in surgery nor recovery delay of anesthesia.
Key words: Cholecystectomy laparoscopy/adv eff    Droperidol/admin    Nausea/prev    Vomiting/prev
收稿日期: 1997-09-02 出版日期: 1998-07-25
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周大春
陈洁
伍伟明

引用本文:

周大春, 陈洁, 伍伟明. 小剂量氟哌啶预防腹腔镜胆囊摘除术后恶心呕吐的研究[J]. 浙江大学学报（医学版）, 1998, 27(4): 157-159.

Zhou Dachun, Chen Jie, Wu Weiming. Low-Dose Droperidol Prevents Postoperative Nausea and Vomiting after Laparoscopic Cholecystectomy. Journal of ZheJiang University(Medical Science), 1998, 27(4): 157-159.

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https://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.1998.04.005    或    https://www.zjujournals.com/med/CN/Y1998/V27/I4/157

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