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叶酸修饰壳聚糖纳米载药胶束的制备及其体外抗肿瘤效果研究 |
刘露1,2( ),黄国俊1,白宏震1,汤谷平1,*( ) |
1. 浙江大学化学系, 浙江 杭州 310028 2. 浙江圣达生物药业股份有限公司, 浙江 台州 317200 |
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Synthesis of folate modified chitosan-based nanomicelles and its in vitro anti-tumor activity |
LIU Lu1,2( ),HUANG Guojun1,BAI Hongzhen1,TANG Guping1,*( ) |
1. Department of Chemistry, Zhejiang University, Hangzhou 310028, China 2. Zhejiang Shengda Bio-pharm Co., Ltd., Taizhou 317200, Zhejiang Province, China |
引用本文:
刘露,黄国俊,白宏震,汤谷平. 叶酸修饰壳聚糖纳米载药胶束的制备及其体外抗肿瘤效果研究[J]. 浙江大学学报(医学版), 2020, 49(3): 364-374.
LIU Lu,HUANG Guojun,BAI Hongzhen,TANG Guping. Synthesis of folate modified chitosan-based nanomicelles and its in vitro anti-tumor activity. J Zhejiang Univ (Med Sci), 2020, 49(3): 364-374.
链接本文:
http://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.2020.06.03
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http://www.zjujournals.com/med/CN/Y2020/V49/I3/364
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1 |
GU F , ZHANG L , TEPLY B A et al. Precise engineering of targeted nanoparticles by using self-assembledbiointegrated block copolymers[J]. Proc Natl Acad Sci U S A, 2008, 105 (7): 2586- 2591
doi: 10.1073/pnas.0711714105
|
2 |
LEAMON C P , REDDY J A . Folate-targeted chemotherapy[J]. Adv Drug Deliv Rev, 2004, 56 (8): 1127- 1141
doi: 10.1016/j.addr.2004.01.008
|
3 |
HILGENBRINK A R , LOW P S . Folate receptor-mediated drug targeting:from therapeutics to diagnostics[J]. J Pharm Sci, 2005, 94 (10): 2135- 2146
doi: 10.1002/jps.20457
|
4 |
ROSS J F , CHAUDHURI P K , RATNAM M . Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications[J]. Cancer, 1994, 73 (9): 2432- 2443
doi: 10.1002/1097-0142(19940501)73:9<2432::aid-cncr2820730929>3.0.co;2-s
|
5 |
WEITMAN S D , LARK R H , CONEY L R et al. Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues[J]. Cancer Res, 1992, 52 (12): 3396- 3401
|
6 |
PAN X Q , LEE R J . In vivo antitumor activity of folate receptor-targeted liposomal daunorubicin in a murine leukemia model[J]. Anticancer Res, 2005, 25 (1A): 343- 346
|
7 |
HE Z , HUANG J , XU Y et al. Co-delivery of cisplatin and paclitaxel by folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles for the treatment of non-small lung cancer[J]. Oncotarget, 2015, 6 (39): 42150- 42168
doi: 10.18632/oncotarget.6243
|
8 |
CHEN Y , PENG J , LAI Y et al. Ultrasensitive label-free detection of circulating tumor cells using conductivity matching of two-dimensional semiconductor with cancer cell[J]. Biosens Bioelectron, 2019, 142 111520
doi: 10.1016/j.bios.2019.111520
|
9 |
BITTLEMAN K R , DONG S , ROMAN M et al. Folic acid-conjugated cellulose nanocrystals show high folate-receptor binding affinity and uptake by KB and breast cancer cells[J]. ACS Omega, 2018, 3 (10): 13952- 13959
doi: 10.1021/acsomega.8b01619
|
10 |
CHEN C , KE J , ZHOU X E et al. Structural basis for molecular recognition of folic acid by folate receptors[J]. Nature, 2013, 500 (7463): 486- 489
doi: 10.1038/nature12327
|
11 |
LOW P S , HENNE W A , DOORNEWEERD D D . Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases[J]. Acc Chem Res, 2008, 41 (1): 120- 129
doi: 10.1021/ar7000815
|
12 |
GAO W , CHAN J M , FAROKHZAD O C . pH-Responsive nanoparticles for drug delivery[J]. Mol Pharm, 2010, 7 (6): 1913- 1920
doi: 10.1021/mp100253e
|
13 |
XIE J , CHEN Z , ZHANG A et al. Folate receptor targeted drug delivery-from the bench to the bedside[J]. J Biomed Mater Res, 2016, 2 (1): 46- 52
doi: 10.18088/ejbmr.2.1.2016.pp46-52
|
14 |
OZA A M , VERGOTE I B , GILBERT L G et al. A randomized double-blind phase Ⅲ trial comparingvintafolide (EC145) and pegylated liposomal doxorubicin (PLD/Doxil?/Caelyx?) in combination versus PLD in participants with platinum-resistant ovarian cancer (PROCEED)(NCT01170650)[J]. Gynecologic Oncology, 2015, 137 5- 6
doi: 10.1016/j.ygyno.2015.01.010
|
15 |
LEAMON C P , PARKER M A , VLAHOV I R et al. Synthesis and biological evaluation of EC20:a new folate-derived, (99m)Tc-based radiopharmaceutical[J]. Bioconjug Chem, 2002, 13 (6): 1200- 1210
doi: 10.1021/bc0200430
|
16 |
REDDY J A , DORTON R , BLOOMFIELD A et al. Pre-clinical evaluation of EC1456, a folate-tubulysin anti-cancer therapeutic[J]. Sci Rep, 2018, 8 (1): 8943
doi: 10.1038/s41598-018-27320-5
|
17 |
MOORE K N , MARTIN L P , O'MALLEY D M et al. Safety and activity of mirvetuximab soravtansine (IMGN853), a folate receptor alpha-targeting antibody-drug conjugate, in platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer:a phase I expansion study[J]. J Clin Oncol, 2017, 35 (10): 1112- 1118
doi: 10.1200/JCO.2016.69.9538
|
18 |
MANSOURI S , CUIE Y , WINNIK F et al. Characterization of folate-chitosan-DNA nanoparticles for gene therapy[J]. Biomaterials, 2006, 27 (9): 2060- 2065
doi: 10.1016/j.biomaterials.2005.09.020
|
19 |
WEN H , YIN C , DU A et al. Folate conjugated PEG-chitosan/graphene oxide nanocomplexes as potential carriers for pH-triggered drug release[J]. J Control Release, 2015, 213 e44- e45
doi: 10.1016/j.jconrel.2015.05.072
|
20 |
JOHN A A , JAGANATHAN S , MANIKANDAN D A et al. Folic acid decorated chitosan nanoparticles and its derivatives for the delivery of drugs and genes to cancer cells[J]. Current Science, 2017, 113 1530- 1542
doi: 10.18520/cs/v113/i08/1530-1542
|
21 |
DING Y , YIN H , CHEN R et al. Carboxymethyl chitosan based nanocomposites containing chemically bonded quantum dots and magnetic nanoparticles[J]. Applied Surface Science, 2018, 433 188- 196
doi: 10.1016/j.apsusc.2017.09.217
|
22 |
BIDKAR A P , SANPUI P , GHOSH SS . Combination therapy with MAPK-pathway specific inhibitor and folic acid receptor targeted selenium nanoparticles induces synergistic anti-proliferative response in BRAF-mutant cancer cells[J]. Acs Biomater-Sci Eng, 2019, 5 (5): 2222- 2234
doi: 10.1021/acsbiomaterials.9b00112
|
23 |
ZHANG S , LIU Y , GAN Y et al. Conjugates of TAT and folate with DOX-loaded chitosan micelles offer effective intracellular delivery ability[J]. Pharm Dev Technol, 2019, 24 (2): 253- 261
doi: 10.1080/10837450.2018.1469147
|
24 |
MARY LAZER L , SADHASIVAM B , PALANIYANDI K et al. Chitosan-based nano-formulation enhances the anticancer efficacy of hesperetin[J]. Int J Biol Macromol, 2018, 107 (Pt B): 1988- 1998
doi: 10.1016/j.ijbiomac.2017.10.064
|
25 |
TORCHILIN V P . Micellar nanocarriers:pharma-ceutical perspectives[J]. Pharm Res, 2007, 24 (1): 1- 16
doi: 10.1007/s11095-006-9132-0
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