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人源瞬时受体电位M2型通道Nudix水解酶9同源结构域的提取和纯化 |
叶培武1( ) |
1. 浙江大学医学院生物物理系, 浙江 杭州 310058 2. 浙江大学医学院蛋白质平台, 浙江 杭州 310058 |
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Extraction and purification of NUDT9 homology domain of human transient receptor potential melastatin 2 channel |
YE Peiwu1( ),YU Xiafei1,MA Cheng2,YANG Wei1( ) |
1.Department of Biophysics, Zhejiang University School of Medicine, Hangzhou 310058, China 2.Protein Facility, Zhejiang University School of Medicine, Hangzhou 310058, China |
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PERRAUD A L , FLEIG A , DUNN C A , et al . ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology[J]. Nature,2001,411(6837):595-599.
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SANO Y , INAMURA K , MIYAKE A , et al . Immunocyte Ca2+ influx system mediated by LTRPC2[J]. Science,2001,293(5533):1327-1330.
|
3 |
BUELOW B , UZUNPARMAK B , PADDOCK M , et al . Structure/function analysis of PARP-1 in oxidative and nitrosative stress-induced monomeric ADPR formation[J/OL]. PLoS One,2009,4(7):e6339.
|
4 |
ZHU Y , ZHAO K K , TONG Y , et al . Exogenous NAD(+) decreases oxidative stress and protects H2O2-treated RPE cells against necrotic death through the up-regulation of autophagy[J]. Sci Rep,2016,6:26322.
|
5 |
KüHN F , KüHN C , LüCKHOFF A . Different principles of ADP-ribose-mediated activation and opposite roles of the NUDT9 homology domain in the TRPM2 orthologs of man and sea anemone[J]. Front Physiol,2017,8:879.
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BESSMAN M J , FRICK D N , O'HANDLEY S F . The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes[J]. J Biol Chem,1996,271(41):25059-25062.
|
7 |
D?LLE C , RACK J G , ZIEGLER M . NAD and ADP-ribose metabolism in mitochondria[J]. FEBS J,2013,280(15):3530-3541.
|
8 |
KISS B , SZáNTó M , SZKLENáR M , et al . Poly(ADP) ribose polymerase-1 ablation alters eicosanoid and docosanoid signaling and metabolism in a murine model of contact hypersensitivity[J]. Mol Med Rep,2015,11(4):2861-2867.
|
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CARLOTO A , COSTAS M J , CAMESELLE J C , et al . The specific, submicromolar-Km ADP-ribose pyrophosphatase purified from human placenta is enzymically indistinguishable from recombinant NUDT9 protein, including a selectivity for Mn2+ as activating cation and increase in Km for ADP-ribose, both elicited by H2O2 [J]. Biochim Biophys Acta,2006,1760(10):1545-1551.
|
10 |
JAMBUNATHAN N , PENAGANTI A , TANG Y , et al . Modulation of redox homeostasis under suboptimal conditions by Arabidopsis nudix hydrolase 7[J]. BMC Plant Biol,2010,10:173.
|
11 |
YU P , XUE X , ZHANG J , et al . Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2[J]. J Gen Physiol,2017,149(2):219-235.
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ZHANG Z , TóTH B , SZOLLOSI A , et al . Structure of a TRPM2 channel in complex with Ca2 + explains unique gating regulation[J/OL]. Elife,2018,7:e36409.
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