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浙江大学学报（医学版）
浙江大学学报（医学版）  2017, Vol. 46 Issue (5): 455-461    DOI: 10.3785/j.issn.1008-9292.2017.10.01
精准影像医学专题     
影像学在肿瘤精准医疗时代的机遇和挑战
许晶晶, 谭延斌, 张敏鸣
浙江大学医学院附属第二医院放射科, 浙江 杭州 310009
Medical imaging in tumor precision medicine: opportunities and challenges
XU Jingjing, TAN Yanbin, ZHANG Minming
Department of Radiology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China
 全文: PDF(932 KB)  
摘要：

肿瘤的精准医疗是将个体化的差异包括环境、生活方式及基因等信息纳入肿瘤诊断、治疗和预防的新兴方法。在过去的几十年，成像设备和对比剂的更新、成像序列标准化、图像分析技术以及多模态成像融合技术的发展成为肿瘤精准医疗的基础。随着自动化、可重复科学算法的应用，肿瘤影像定量特征的不断提取，肿瘤临床和影像数据库被不断挖掘和开发，影像基因组学、影像组学和影像大数据人工智能得到了蓬勃发展。这些新的技术进步为影像学在肿瘤精准医疗中的应用带来新的机遇和挑战。
关键词： 肿瘤;  人工智能;  诊断显像;  综述;  治疗,计算机辅助;  基因组学    
Abstract:

Tumor precision medicine is an emerging approach for tumor diagnosis, treatment and prevention, which takes account of individual variability of environment, lifestyle and genetic information. Tumor precision medicine is built up on the medical imaging innovations developed during the past decades, including the new hardware, new imaging agents, standardized protocols, image analysis and multimodal imaging fusion technology. Also the development of automated and reproducible analysis algorithm has extracted large amount of information from image-based features. With the continuous development and mining of tumor clinical and imaging databases, the radiogenomics, radiomics and artificial intelligence have been flourishing. Therefore, these new technological advances bring new opportunities and challenges to the application of imaging in tumor precision medicine.
Key words: Artificial intelligence    Therapy,computer-assisted    Diagnostic imaging    Review    Genomics    Neoplasms
收稿日期: 2017-09-30 出版日期: 2017-10-25
CLC:  R445  
基金资助:

浙江省医药卫生科技计划（2017205359）；国家重点研发计划（2016YFC13066）；国家卫生和计划生育委员会科研基金（2016149022）；国家自然科学基金（8157165）
通讯作者: 张敏鸣(1957-),女,博士,教授,主任医师,博士生导师,主要从事神经退行性疾病的多模态影像和肿瘤精准影像学研究;E-mail:zhangminming@zju.edu.cn;http://orcid.org/0000-0003-0145-7558     E-mail: zhangminming@zju.edu.cn
作者简介: 许晶晶(1985-),女,博士研究生,主治医师,主要从事放射诊断和研究;E-mail:mcdxjj@163.com;http://orcid.org/0000-0003-4779-1981
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引用本文:

许晶晶 等. 影像学在肿瘤精准医疗时代的机遇和挑战[J]. 浙江大学学报（医学版）, 2017, 46(5): 455-461.

XU Jingjing, TAN Yanbin, ZHANG Minming. Medical imaging in tumor precision medicine: opportunities and challenges. Journal of ZheJiang University(Medical Science), 2017, 46(5): 455-461.

链接本文:

http://www.zjujournals.com/xueshu/med/CN/10.3785/j.issn.1008-9292.2017.10.01    或    http://www.zjujournals.com/xueshu/med/CN/Y2017/V46/I5/455

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