[1] CONLEY-LACOMB M K, SALIGANAN A, KANDAGATLA P, et al. PTEN loss mediated Akt activation promotes prostate tumor growth and metastasis via CXCL12/CXCR4 signaling[J]. Mol Cancer,2013,12(1):85.
[2] FENG B, LI K, ZHONG H, et al. RhoE promotes metastasis in gastric cancer through a mechanism dependent on enhanced expression of CXCR4[J/OL]. PLoS One,2013,8(11):e81709.
[3] LIAO Y X, ZHOU C H, ZENG H, et al. The role of the CXCL12-CXCR4/CXCR7 axis in the progression and metastasis of bone sarcomas(review)[J]. Int J Mol Med,2013,32(6):1239-1246.
[4] YANG P, LIANG S X, HUANG W H, et al. Aberrant expression of CXCR4 significantly contributes to metastasis and predicts poor clinical outcome in breast cancer[J]. Curr Mol Med,2014,14(1):174-184.
[5] YANG Q, ZHANG F, DING Y,et al. Antitumour activity of the recombination polypeptide GST-NT21MP is mediated by inhibition of CXCR4 pathway in breast cancer[J]. Br J Cancer,2014,110(5):1288-1297.
[6] SONODA H, INOUE H, OGAWA K, et al.Significance of skp2 expression in primary breast cancer[J]. Clin Cancer Res,2006,12(4):1215-1220.
[7] LU Z, HUNTER T. Ubiquitylation and proteasomal degradation of the p21Cip1, p27Kip1 and p57Kip2 CDK inhibitors[J]. Cell Cycle,2010,9(12):2342-2352.
[8] YANG QL, ZHANG LY, WANG HF, et al. The N-terminal polypeptide derived from viral macrophage inflammatory protein Ⅱ reverses breast cancer epithelial-omesenchymal transition via a PDGFRa-dependent mechanism[J]. Oncotarge,2017,8(23):37448-37463.
[9] CHATTERJEE S, BEHNAM AZAD B, NIMMAGADDA S. The intricate role of CXCR4 in cancer[J]. Adv Cancer Res,2014,124:31-82.
[10] BAJETTO A, BARBIERI F, PATTAROZZI A, et al. CXCR4 and SDF1 expression in human meningiomas:a proliferative role in tumoral meningothelial cells in vitro[J]. Neuro Oncol,2007,9(1):3-11.
[11] ZHENG Q, SHUAI X, YE Y, et al. The role of polymorphisms of stromal derived factor-1 and CXC receptor 4 in acute myeloid leukemia and leukemia cell dissemination[J]. Gene,2016,588(2):103-108.
[12] 袁宏,冯虎,家秀秀,等.CXCR4 shRNA对U87胶质瘤细胞周期和凋亡的影响[J].中国热带医学,2015,15(1):25-27. YUAN Hong, FENG Hu, JIA Xiuxiu, et al. Effects of CXCR4 shRNA on cell cycle and apoptosis of U87 glioma[J]. China Tropical Medicine,2015,15(1):25-27. (in Chinese)
[13] 王艳,刘晓日,谭艳芳,等.RNA干扰沉默CXCR4基因对Jurkat细胞周期和凋亡的影响[J].中国实验血液学杂志,2010,18(3):625-628. WANG Yan, LIU Xiaori, TAN Yanfang, et al. Effects of CXCR4 silence induced by RNA interference on cell cycle distribution and apoptosis of jurkat cells[J]. Journal of Experimental Hematology,2010,18(3):625-628. (in Chinese)
[14] YANG Q, WU H, WANG H, et al. N-terminal polypeptide derived from vMIP-Ⅱ exerts its antitumor activity by inhibiting the CXCR4 pathway in human glioma[J]. Int J Oncol,2017,50(4):1160-1174.
[15] DEMETRICK D J, ZHANG H, BEACH D H. Chromosomal mapping of the genes for the human CDK2/cyclin A-associated proteins p19(SKP1A and SKP1B) and p45(SKP2)[J]. Cytogenet Cell Genet,1996,73(1-2):104-107.
[16] ZHANG H, KOBAYASHI R, GALAKTIONOV K, et al. p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase[J]. Cell,1995,82(6):915-925.
[17] CHAN C H, MORROW J K, ZHANG S, et al. Skp2:a dream target in the coming age of cancer therapy[J]. Cell Cycle,2014,13(5):679-680.
[18] PATERAS I S, APOSTOLOPOULOU K, KOUTSAMI M, et al. Downregulation of the KIP family members p27(KIP1) and p57(KIP2) by SKP2 and the role of methylation in p57(KIP2) inactivation in nonsmall cell lung cancer[J]. Int J Cancer,2006,119(11):2546-2556.
[19] FRESCAS M, PAGANO M. Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP:tipping the scales of cancer[J]. Nat Rev Cancer,2008,8(6):438-449.
[20] ZHOU W, SRINIVASAN S, NAWAZ Z, et al. ERα, SKP2 and E2F-1 form a feed forward loop driving late ERα targets and G1 cell cycle progression[J]. Oncogene,2014,33(18):2341-2353.
[21] WANG G, CHAN C H, GAO Y, et al. Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis[J]. Chin J Cancer,2012,31(4):169-177.
[22] MITREA D M, YOON M K, OU L, et al. Disorder-function relationships for the cell cycle regulatory proteins p21 and p27[J]. Biol Chem,2012,393(4):259-274.
[23] 赵君,杨春鹿,赵苏英.肺癌中细胞S期激酶相关蛋白2的表达及其对预后的影响[J].中华肿瘤杂志,2007,29(4):289-292. ZHAO Jun, YANG Chunlu, ZHAO Suying. Expression of Skp2 protein in lung carcinoma and its implication for prognosis[J]. Chinese Journal of Oncology,2007,29(4):289-292. (in Chinese)
[24] WESTERMANN F, HENRICH K O, WEI J S, et al. High Skp2 expression characterizes high-risk neuroblastomas independent of MYCN status[J]. Clin Cancer Res,2007,13(16):4695-4703.
[25] YANG Q, HUANG J, WU Q, et al.Acquisition of epithelial-mesenchymal transition is associated with Skp2 expression in paclitaxel-resistant breast cancer cells[J]. Br J Cancer,2014,110(8):1958-1967.
[26] DOUGLASS S, MEESON A P, OVERBECK-ZUBRZYCKA D, et al. Breast cancer metastasis:demonstration that FOXP3 regulates CXCR4 expression and the response to CXCL12[J]. J Pathol,2014,234(1):74-85.
[27] LIN H K, WANG G, CHEN Z, et al. Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB[J]. Nat Cell Biol,2009,11(4):420-432.
[28] GAO D, INUZUKA H, TSENG A, et al. Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction[J]. Nat Cell Biol,2009,11(4):397-408.
[29] YANG Q, CHEN C, YANG Z, et al. Suppression of breast cancer proliferation and induction of apoptosis via AKT and ERK1/2 signal transduction pathways by synthetic polypeptide derived from viral macrophage inflammatory protein Ⅱ[J]. J Huazhong Univ Sci Technolog Med Sci,2011,31(4):497-503. |