碘131联合射频消融治疗儿童甲状腺功能亢进症伴重度甲状腺肿一例

doi:10.3785/j.issn.1008-9292.2017.02.13

浙江大学学报（医学版）

2017, Vol. 46

Issue (1): 89-91 DOI: 10.3785/j.issn.1008-9292.2017.02.13

病例报告

碘131联合射频消融治疗儿童甲状腺功能亢进症伴重度甲状腺肿一例

陈永花¹(

),梁黎^1,^*(

),方燕兰¹,王春林¹,李林法²,蒋天安³

⁽¹⁾ 浙江大学医学院附属第一医院儿科, 浙江杭州 310003
⁽²⁾ 浙江大学医学院附属第一医院核医学科, 浙江杭州 310003
⁽³⁾ 浙江大学医学院附属第一医院超声影像科, 浙江杭州 310003

Iodine 131 joint radio frequency ablation treatment for child with hyperthyroidism goiter: one case report

CHEN Yonghua¹(

),LIANG Li^1,^*(

),FANG Yanlan¹,WANG Chunlin¹,LI Linfa²,JIANG Tian'an³

⁽¹⁾ Department of Pediatrics, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
⁽²⁾ Department of Nuclear Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
⁽³⁾ Department of Ultrasonography, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China

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摘要：

一例12岁8个月女童，发现颈部肿块5年余，喉部不适、呼吸困难一周入院。患儿5年前被诊断为“桥本甲状腺炎、甲状腺功能亢进症”，药物治疗后甲状腺功能仍有波动。本次入院后颈部超声检查提示左侧甲状腺大小为8.1 cm×3.2 cm，右侧为8.2 cm×4.8 cm。行碘131联合射频消融治疗后，患儿喉部不适、呼吸困难症状消失，超声检查提示左侧甲状腺缩小至2.3 cm×1.7 cm，右侧缩小至2.8 cm×2.0 cm。随访两年半，无复发。

关键词： 碘放射性同位素/治疗应用; 导管消融术; 甲状腺功能亢进症/药物疗法; 甲状腺肿/药物疗法; 甲状腺肿/并发症; 危重病; 儿童; 病例报告

Abstract:

A 12-year-old girl presented with a history of cervical mass, and one week of throat discomfort and dyspnea. Five years ago, the patient was diagnosed as Hashimoto's thyroiditis and hyperthyroidism; she received antithyroid drug treatment, but the result was not satisfactory. B-ultrasonic showed that the size of thyroid gland was 8.1 cm×3.2 cm in the left and 8.2 cm×4.8 cm in the right. After iodine 131 combined with radiofrequency ablation (RFA) treatment, throat discomfort and recumbent breathing difficulties disappeared, and B-ultrasonic showed that the size of thyroid reduced to 2.3 cm×1.7 cm (left) and 2.8 cm×2.0 cm (right). No recurrence was observed during the two and a half years of follow-up.

Key words: Iodine radioisotopes/therapeutic use Catheter ablation Hyperthyroidism/drug therapy Goiter/drug therapy Goiter/complications Critical illness Child Case reports

收稿日期: 2016-10-16 出版日期: 2017-07-06

CLC:

R725.8

基金资助: 浙江省医药卫生科技计划(2016ZHA004)

通讯作者: 梁黎 E-mail: 21518037@zju.edu.cn;zdliangli@163.com

作者简介: 陈永花 (1990-), 女, 硕士研究生, 住院医师, 主要从事儿科内分泌临床与基础研究工作; E-mail:21518037@zju.edu.cn|梁黎 (1956-), 女, 硕士, 教授, 博士生导师, 主要从事儿科内分泌临床与基础研究工作; E-mail:zdliangli@163.com

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引用本文:

陈永花,梁黎,方燕兰,王春林,李林法,蒋天安. 碘131联合射频消融治疗儿童甲状腺功能亢进症伴重度甲状腺肿一例[J]. 浙江大学学报（医学版）, 2017, 46(1): 89-91.

CHEN Yonghua,LIANG Li,FANG Yanlan,WANG Chunlin,LI Linfa,JIANG Tian'an. Iodine 131 joint radio frequency ablation treatment for child with hyperthyroidism goiter: one case report. J Zhejiang Univ (Med Sci), 2017, 46(1): 89-91.

链接本文:

http://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.2017.02.13 或 http://www.zjujournals.com/med/CN/Y2017/V46/I1/89

表1 碘131和射频消融治疗前后超声检查甲状腺大小变化

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5	章建全, 马娜, 徐斌 et al. 超声引导监测下经皮射频消融甲状腺腺瘤的方法学研究. 中华超声影像学杂志. 2010, 19(10): 861-865 doi: 10.3760/cma.j.issn.1004-4477.2010.10.011 ZHANG Jianquan, MA Na, XU Bin et al. Methodology of percutaneous bi-polar radiofrequency ablation of thyroid adenomas under ultrasound guidance and monitoring. Chinese Journal of Ultrasonography. 2010, 19(10): 861-865 doi: 10.3760/cma.j.issn.1004-4477.2010.10.011

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